Ota M, Sato N, Sone D, Ogura J, Kunugi H Indian Journal of Psychiatry, 2017 BACKGROUND: Although aromatherapy is widely used, the pharmacology of the essential oils remains undiscovered. AIM: The present study assessed the effect of (-)-linalool, the main contained material of lavender, on the brain function. MATERIALS AND METHODS: Healthy male volunteers calculated… Read more »
Topical Menthol for Treatment of Chemotherapy-induced Peripheral Neuropathy
Cortellini A, Verna L, Cannita K, Napoleoni L, Parisi A, Ficorella C, Porzio G Indian Journal of Palliative Care, 2017 ABSTRACT: Chemotherapy-induced peripheral neuropathy is a frequent treatment-limiting factor that significantly impairs patients’ everyday life, also because of a lack of valid palliative options. Here, we report a case of a male patient with a history of metastatic… Read more »
Carvacrol promotes angiogenic paracrine potential and endothelial differentiation of human mesenchymal stem cells at low concentrations
Matluobi D, Araghi A, Maragheh BFA, Rezabakhsh A, Soltani S, Khaksar M, Siavashi V, Feyzi A, Bagheri HS, Rahbarghazi R, Montazersaheb S Microvascular Research, 2017 OBJECTIVES: Phenolic monoterpene compound, named Carvacrol, has been found to exert different biological outcomes. It has been accepted that the angiogenic activity of human mesenchymal stem cells was crucial in the… Read more »
Combination treatment of citral potentiates the efficacy of hyperthermic intraperitoneal chemoperfusion with pirarubicin for colorectal cancer
Fang Z, Wang Y, Li H, Yu S, Liu Z, Fan Z, Chen X, Wu Y, Pan X, Li X, Wang C Molecular Pharmacology, 2017 ABSTRACT: Citral is a widely used penetration enhancer that has been used to assist the delivery of drugs through the skin. In this study we aimed to investigate the effectiveness of… Read more »
Critical synergistic concentration of lecithin phospholipids improve the antimicrobial activity of eugenol against Escherichia coli
Zhang H, Dudley EG, Harte F Applied Environmental Microbiology, 2017 ABSTRACT: In this study, the effect of individual lecithin phospholipids on the antimicrobial properties of eugenol against E. coli C600 was investigated. We tested five major phospholipids common in soy or egg lecithin (DPPC, DSPC, DPPE, DPPA and DPPS) and one synthetic cationic phospholipid (EPC 18:0). Among six phospholipids,… Read more »
Olfactory receptor 10J5 responding to α-cedrene regulates hepatic steatosis via the cAMP-PKA pathway
Tong T, Ryu SE, Min Y, de March CA, Bushdid C, Golebiowski J, Moon C, Park T Scientific Reports, 2017 ABSTRACT: Ectopic expression and functions of odorant receptors (ORs) in the human body have aroused much interest in the past decade. Mouse olfactory receptor 23 (MOR23, olfr16) and its human orthologue, OR10J5, have been found… Read more »
Chemical Composition of Pinus roxburghii Bark Volatile Oil and Validation of Its Anti-Inflammatory Activity Using Molecular Modelling and Bleomycin-Induced Inflammation in Albino Mice
Labib RM, Youssef FS, Ashour ML, Abdel-Daim MM, Ross SA Molecules, 2017 ABSTRACT: The chemical composition of Pinus roxburghii bark essential oil (PRO) was qualitatively and quantitatively determined using GC/FID and GC/MS. The anti-inflammatory activity was assessed in vitro by evaluating the binding percentages on the cannabinoids and opioids receptors. Bleomycin (BLM)-induced pulmonary inflammation in albino mice was adopted… Read more »
Aromatic-turmerone Attenuates LPS-Induced Neuroinflammation and Consequent Memory Impairment by Targeting TLR4-Dependent Signaling Pathway
Chen M, Chang YY, Huang S, Xiao LH, Zhou W, Zhang LY, Li C, Zhou RP, Tang J, Lin L, Du ZY, Zhang K Molecular Nutrition and Food Research, 2017 SCOPE: Curcuma longa (turmeric) is a folk medicine in South and Southeast Asia, which has been widely used to alleviate chronic inflammation. Aromatic-turmerone is one… Read more »
Cytotoxicity of the Essential Oil of Fennel (Foeniculum vulgare) from Tajikistan
Sharopov F, Valiev A, Satyal P, Gulmurodov I, Yusufi S, Setzer WN, Wink M Foods, 2017 ABSTRACT: The essential oil of fennel (Foeniculum vulgare) is rich in lipophilic secondary metabolites, which can easily cross cell membranes by free diffusion. Several constituents of the oil carry reactive carbonyl groups in their ring structures. Carbonyl groups can… Read more »
In Vitro Antibacterial and Antibiofilm Activity of Lippia alba Essential Oil, Citral, and Carvone against Staphylococcus aureus
Porfírio EM, Melo HM, Pereira AMG, Cavalcante TTA, Gomes GA, de Carvalho MG, Costa RA, Júnior FEAC ScientificWorld Journal, 2017 ABSTRACT: In vitro antimicrobial and antibiofilm activities of the Lippia alba essential oil and its major components (citral and carvone) against Staphylococcus aureus were investigated. Essential oils (LA1EO, LA2EO, and LA3EO) were extracted from the aerial parts of three L…. Read more »