Beta-elemene

  • Backbone: Sesquiterpene
  • Functional Group: None

Nigella damascena L. essential oil and its main constituents, damascenine and β-elemene modulate inflammatory response of human neutrophils ex vivo

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Sieniawska E, Michel P, Mroczek T, Granica S, Skalicka-woźniak K Food and Chemical Toxicology, 2019 ABSTRACT: Nigella damascena L belongs to Ranunculaceae family and is mentioned in Eastern traditional medicine for the treatment of high temperatures, regulation of menstruation or catarrhal affections. The anti-inflammatory activity of compounds present in the essential oil obtained from seeds… Read more »

β-elemene regulates endoplasmic reticulum stress to induce the apoptosis of NSCLC cells through PERK/IRE1α/ATF6 pathway

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Liu Y, Jiang ZY, Zhou Y, Qiu HH, Wang G, Luo Y, Liu JB, Liu XW, Bu WQ, Song J, Cui L, Jia XB, Feng L Biomedicine & Pharmacotherapy, 2017 ABSTRACT: Endoplasmic reticulum stress (ERs) has been regarded as an important cause for the pathogenesis of non-small-cell lung cancer (NSCLC). β-elemene is an active component in the essential oil extracted from a medicinal herb, Curcuma wenyujin, and has been… Read more »

Furanodiene enhances the anti-cancer effects of doxorubicin on ERα-negative breast cancer cells in vitro

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Zhong ZF, Qiang WA, Wang CM, Tan W, Wang YT European journal of pharmacology, 2016 ABSTRACT: Furanodiene is a natural product isolated from Rhizoma curcumae, and exhibits broad-spectrum anti-cancer activities in vitro and in vivo. Our previous study proved that furanodiene could increase growth inhibition of steroidal agent in ERα-positive breast cancer cells, but whether… Read more »