Amiresmaeili A, Roohollahi S, Mostafavi A, Askari N Research in Pharmaceutical Sciences, 2018 ABSTRACT: The aim of the present study was to evaluate the effects of oregano essential oil (OEO) on the hippocampus and prefrontal cortex TLR 2/4 gene expression and depressive like behavior induced by chronic unpredictable stress (CUS). Sucrose preference and forced swim… Read more »
Carvacrol
- Backbone: Monoterpene
- Functional Group: Phenol
Terpenes, Phenylpropanoids, Sulfur and Other Essential Oil Constituents as Inhibitors of Cholinesterases
Politeo O, Burcul F, Blazevic I, Radan M Current Medicinal Chemistry, 2018 ABSTRACT: Essential oils constituents are a diverse family of low molecular weight organic compounds with comprehensive biological activity. According to their chemical structure these active compounds can be divided into four major groups: terpenes, terpenoids, phenylpropenes, and “others”. In addition, they may contain… Read more »
Citrus fruit extracts with carvacrol and thymol eliminated 7-log acid-adapted Escherichia coli O157:H7, Salmonella typhimurium, and Listeria monocytogenes: A potential of effective natural antibacterial agents
Chung D, Cho TJ, Rhee MS Food Research International, 2018 ABSTRACT: Despite the widespread belief that citrus fruit extracts (CFEs) are microbiologically safe due to their acidity, limited bactericidal effect results in low applicability as antibacterial agent and outbreaks occurred by acid-adapted pathogens. Here, we examined the antibacterial effects of CFEs [lime (Citrus medica), lemon… Read more »
Structure-activity modelling of essential oils, their components, and key molecular parameters and descriptors
Owen L, Laird K, Wilson PB Molecular and Cellular Probes, 2017 ABSTRACT: Many essential oil components are known to possess broad spectrum antimicrobial activity, including against antibiotic resistant bacteria. These compounds may be a useful source of new and novel antimicrobials. However, there is limited research on the structure-activity relationship (SAR) of essential oil compounds,… Read more »
Effects of patchouli and cinnamon essential oils on biofilm and hyphae formation by Candida species
Farisa Banu S, Rubini D, Shanmugavelan P, Murugan R, Gowrishankar S, Karutha Pandian S, Nithyanand P Journal de Mycologie Medicale, 2018 ABSTRACT: The prevalence and fatality rates with biofilm-associated candidal infections have remained a challenge to the medical fraternity despite major advances in the field of antifungal therapy. Traditionally, essential oils (EOs) from the aromatic… Read more »
Use of micronucleus and comet assay to evaluate evaluate the genotoxicity of oregano essential oil (Origanum vulgare l. Virens) in rats orally exposed for 90 days
Llana-Ruiz-Cabello M, Puerto M, Maisanaba S, Guzmán-Guillén R, Pichardo S, Cameán AM Journal of Toxicology and Environmental Health Part A, 2018 ABSTRACT: Essential oils from Origanum spp. exhibit antioxidant and antimicrobial activities making them suitable for use as food additives. The incorporation of oregano essential oil in active food packaging is under study; however, it… Read more »
Efficacy of poly(lactic acid)/carvacrol electrospun membranes against Staphylococcus aureus and Candida albicans in single and mixed cultures
Scaffaro R, Lopresti F, D’Arrigo M, Marino A, Nostro A Applied Microbiology and Biotechnology, 2018 ABSTRACT: Carvacrol (CAR) is one of the most promising essential oil components with antimicrobial activity. New technologies aimed to incorporate this active molecule into carrier matrix to improve the stability and prolong the biological activity. The goal of this study… Read more »
Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano (Origanum vulgare) essential oil in a human skin disease model
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: The use of oregano (Origanum vulgare) essential oil (OEO) has become popular in skin care products. However, scientific research regarding its effects on human skin cells is scarce. In this study, we investigated the biological activity of a commercially available OEO, which is high in carvacrol content,… Read more »
Evaluation of anti-enzyme properties of Origanum vulgare essential oil against oral Candida albicans
Pradebon Brondani L, Alves da Silva Neto T, Antonio Freitag R, Guerra Lund R Journal de Mycologie Medicale, 2018 ABSTRACT: This study aimed to evaluate the anti-enzymatic activity of Origanum vulgare (oregano) essential oil against 15 strains of Candida albicans. Candida albicans samples were isolated from the oral mucosa of patients with denture stomatitis treated… Read more »
Alcoholic monoterpenes found in essential oil of aromatic spices reduce allergic inflammation by the modulation of inflammatory cytokines
Pina LTS, Ferro JNS, Rabelo TK, Oliveira MA, Scotti L, Scotti MT, Walker CIB, Barreto EO, Quintans Júnior LJ, Guimarães AG Natural Product Research, 2018 ABSTRACT: Allergic inflammation is a response of the body against pathogens by cytokine release and leucocyte recruitment. Recently, there was an increase in morbimortality associated with allergic inflammation, especially asthma…. Read more »