Bartoňková I, Dvořák Z Food Chemistry & Toxicology ABSTRACT: Essential oils (EOs) of culinary herbs and spices are used to flavor, color and preserve foods and drinks. Dietary intake of EOs is significant, deserving an attention of toxicologists. We examined the effects of 31 EOs of culinary herbs and spices on the transcriptional activity of human… Read more »
Carvacrol
- Backbone: Monoterpene
- Functional Group: Phenol
Antifungal and Anti-Biofilm Activity of Essential Oil Active Components against Cryptococcus neoformans and Cryptococcus laurentii
Kumari P, Mishra R, Arora N, Chatrath A, Gangwar R, Roy P, Prasad R Frontiers in Microbiology, 2017 ABSTRACT: Cryptococcosis is an emerging and recalcitrant systemic infection occurring in immunocompromised patients. This invasive fungal infection is difficult to treat due to the ability of Cryptococcus neoformans and Cryptococcus laurentii to form biofilms resistant to standard antifungal treatment…. Read more »
Effect of oregano essential oil and carvacrol on Cryptosporidium parvum infectivity in HCT-8 cells
Gaur S, Kuhlenschmidt TB, Kuhlenschmidt MS, Andrade JE Parasitology International, 2017 ABSTRACT: Cryptosporidium parvum is the second leading cause of persistent diarrhea among children in low-resource settings. This study examined the effect of oregano essential oil (OEO) and carvacrol (CV) on inhibition of C. parvum infectivity in vitro. HCT-8 cells were seeded (1×106) in 96-well microtiter plates… Read more »
Proteinaceous microspheres as a delivery system for carvacrol and thymol in antibacterial applications
Sokolik CG, Ben-Shabat-Binyamini R, Gedanken A, Lellouche JP Ultrasonics & Sonochemistry, 2017 ABSTRACT: There is an urgent need for new materials with antimicrobial activity. Phenolic essential oil (EO) compounds with Generally Recognized As Safe (GRAS) status are attractive candidates, but they need suitable delivery systems to overcome specific drawbacks. Core-shell microspheres (MSs) of Bovine Serum Albumin (BSA)… Read more »
Selective Essential Oils from Spice or Culinary Herbs Have High Activity against Stationary Phase and Biofilm Borrelia burgdorferi
Feng J, Zhang S, Shi W, Zubcevik N, Miklossy J, Zhang Y Frontiers in Medicine, 2017 ABSTRACT: Although the majority of patients with acute Lyme disease can be cured with the standard 2-4 week antibiotic treatment, about 10-20% of patients continue suffering from chronic symptoms described as posttreatment Lyme disease syndrome. While the cause for this… Read more »
Carvacrol and eugenol effectively inhibit Rhizopus stolonifer and control postharvest soft rot decay in peaches
Zhou D, Wang Z, Li M, Xing M, Xian T, Tu K Journal of Applied Microbiology AIMS: This study aimed to investigate the antifungal mechanism of carvacrol and eugenol to inhibit Rhizopus stolonifer and the control of postharvest soft rot decay in peaches. METHODS AND RESULTS: For antifungal mechanism, effects of carvacrol and eugenol on… Read more »
Combined Toxicity of Three Essential Oils Against Aedes aegypti (Diptera: Culicidae) Larvae
Muturi EJ, Ramirez JL, Doll KM, Bowman MJ Journal of Medical Entomology, 2017 ABSTRACT: Essential oils are potential alternatives to synthetic insecticides because they have low mammalian toxicity, degrade rapidly in the environment, and possess complex mixtures of bioactive constituents with multi-modal activity against the target insect populations. Twenty-one essential oils were initially screened for their toxicity against… Read more »
Perspectives on medicinal properties of natural phenolic monoterpenoids and their hybrids
Rajput JD, Bagul SD, Pete UD, Zade CM, Padhye SB, Bendre RS Molecular Diversity, 2017 ABSTRACT: Carvacrol, thymol and eugenol belong to a class of naturally presenting phenols with a ten-carbon unit, which are present in essential oils of many plants. These versatile molecules are incorporated as useful ingredients in many food products and find applications in… Read more »
Carvacrol-rich oregano oil and thymol-rich thyme red oil inhibit biofilm formation and the virulence of uropathogenic Escherichia coli
Lee JH, Kim YG, Lee J Journal of Applied Microbiology, 2017 AIMS: Urinary tract infections are caused primarily by uropathogenic Escherichia coli (UPEC), and indwelling catheters are usually colonized by UPEC biofilms tolerant to common antibiotics. Hence, UPEC biofilms pose a substantial challenge, and there is an urgent need for effective control strategies. METHODS AND… Read more »
Toxic and repellent activity of selected monoterpenoids (thymol, carvacrol and linalool) against the castor bean tick, Ixodes ricinus (Acari: Ixodidae)
Tabari MA, Youssefi MR, Maggi F, Benelli G Veterinary Parasitology, 2017 ABSTRACT: The castor bean tick, Ixodes ricinus, is a species of medical and veterinary importance. The use of synthetic acaricides for tick control has led to development of resistance, residues in the environment and animal products, and public health concerns. In this regard, plant essential… Read more »