Chueca B, Pérez-Sáez E, Pagán R, García-Gonzalo D International Journal of Food Microbiology, 2017 ABSTRACT: DNA microarrays were used to study the mechanism of bacterial inactivation by carvacrol and citral. After 10-min treatments of Escherichia coli MG1655 cells with 100 and 50ppm of carvacrol and citral, 76 and 156 genes demonstrated significant transcriptional differences (p≤0.05),… Read more »
Carvacrol
- Backbone: Monoterpene
- Functional Group: Phenol
Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano (Origanum vulgare) essential oil in a human skin disease model
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: The use of oregano (Origanum vulgare) essential oil (OEO) has become popular in skin care products. However, scientific research regarding its effects on human skin cells is scarce. In this study, we investigated the biological activity of a commercially available OEO, which is high in carvacrol content,… Read more »
Essential oils and their constituents as anticancer agents: a mechanistic view
Gautam N, Mantha AK, Mittal S BioMed Research International, 2014 ABSTRACT: Exploring natural plant products as an option to find new chemical entities as anticancer agents is one of the fastest growing areas of research. Recently, in the last decade, essential oils (EOs) have been under study for their use in cancer therapy and the… Read more »
The protective effects of carvacrol and thymol against paracetamol-induced toxicity on human hepatocellular carcinoma cell lines (HepG2)
Palabiyik SS, Karakus E, Halici Z, Cadirci E, Bayir Y, Ayaz G, Cinar I Human & experimental toxicology, 2016 ABSTRACT: Acetaminophen (APAP) overdose could induce liver damage and lead to acute liver failure. The treatment of APAP overdoses could be improved by new therapeutic strategies. Thymus spp., which has many beneficial effects and has been… Read more »
Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol
Khosravi AR, Erle DJ PloS one, 2016 ABSTRACT: Chitin is produced in large amounts by fungi, insects, and other organisms and has been implicated in the pathogenesis of asthma. Airway epithelial cells are in direct contact with environmental particles and serve as the first line of defense against inhaled allergens and pathogens. The potential contributions… Read more »
Plant essential oils for pest and disease management
Murray B Isman Crop Protection, 2000 ABSTRACT: Certain essential plant oils, widely used as fragrances and flavors in the perfume and food industries, have long been reputed to repel insects. Recent investigations in several countries confirm that some plant essential oils not only repel insects, but have contact and fumigant insecticidal actions against specific pests,… Read more »
Inhibition of Staphylococcus aureus cocktail using the synergies of oregano and rosemary essential oils or carvacrol and 1,8-cineole
Honório VG0, Bezerra J, Souza GT, Carvalho RJ, Gomes-Neto NJ, Figueiredo RC, Melo JV, Souza EL, Magnani M Frontiers in microbiology, 2015 ABSTRACT: This study assessed the inhibitory effects of the essential oils (EOs) from Origanum vulgare L. (OVEO) and Rosmarinus officinalis L. (ROEO), as well as of the its majority individual constituents (ICs) carvacrol… Read more »
Larvicidal potential of carvacrol and terpinen-4-ol from the essential oil of Origanum vulgare (Lamiaceae) against Anopheles stephensi, Anopheles subpictus, Culex quinquefasciatus and Culex tritaeniorhynchus (Diptera: Culicidae)
Govindarajan M, Rajeswary M, Hoti SL, Benelli G Research in veterinary science, 2016 ABSTRACT: Mosquito-borne diseases represent a deadly threat for millions of people worldwide. However, the use of synthetic insecticides to control Culicidae may lead to resistance, high operational costs and adverse non-target effects. Nowadays, plant-borne mosquitocides may serve as suitable alternative in the… Read more »
Effects of monoterpenes on ion channels of excitable cells
Oz M, Lozon Y, Sultan A, Yang KH, Galadari S Pharmacology & therapeutics, 2015 ABSTRACT: Monoterpenes are a structurally diverse group of phytochemicals and a major constituent of plant-derived ‘essential oils’. Monoterpenes such as menthol, carvacrol, and eugenol have been utilized for therapeutical purposes and food additives for centuries and have been reported to have… Read more »
Essential oil diversity of European Origanum vulgare L. (Lamiaceae)
Lukas B, Schmiderer C, Novak J
Phytochemistry, 2015