Eucalyptol (1,8-cineole)

  • Backbone: Monoterpene
  • Functional Group: Ether

Evaluation the effect of 50 and 100 mg doses of Cuminum cyminum essential oil on glycemic indices, insulin resistance and serum inflammatory factors on patients with diabetes type II: A double-blind randomized placebo-controlled clinical trial

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Jafari S, Sattari R, Ghavamzadeh S Journal of Traditional and Complementary Medicine, 2017 ABSTRACT: AIM: The purpose of this study was to evaluate the effect of 50 and 100 mg doses of green cumin essential oil on glycemic and inflammatory indices in patients with diabetes type II. METHOD: In this randomized double-blind placebo-controlled clinical trial, subjects were divided into three… Read more »

Anti-inflammatory and antialgic actions of a nanoemulsion of Rosmarinus officinalis L. essential oil and a molecular docking study of its major chemical constituents

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Borges RS, Lima ES, Keita H, Ferreira IM, Fernandes CP, Cruz RAS, Duarte JL, Velázquez-Moyado J, Ortiz BLS, Castro AN, Ferreira JV, da Silva Hage-Melim LI, Carvalho JCT Inflammopharmacology, 2017 ABSTRACT: We evaluate the anti-inflammatory and antialgic potency of a nanoemulsion (NEORO) containing the essential oil of Rosmarinus officinalis L. (EORO), which is composed primarily of limonene, camphor and 1,8-cineole. The EORO and NEORO were administered orally 30 min prior… Read more »

Studies on the Behavior of Eucalyptol and Terpinen-4-ol – Natural Food Additives and Ecological Pesticides – in Model Lipid Membranes

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Hąc-Wydro K, Flasiński M, Broniatowski M, Sołtys M Langmuir, 2017 ABSTRACT: Effective application of the essential oils requires detailed exploration of their mechanism of action and the origin of diverse activity of their components. In this work, the influence of eucalyptol and terpinen-4-ol on artificial membranes was studied to verify whether the differences in the activity of these compounds are… Read more »

Essential oils diversely modulate genome-wide gene expression in human dermal fibroblasts

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Han X, Parker TL Cogent Medicine, 2017 ABSTRACT: The increasing popularity of essential oils for skincare has led to investigation of their biological effects in human skin cells. In this study, we investigated the biological activities of three commercially available essential oils, i.e. rosemary oil, wild orange oil, and a blend (commercial name: Deep Blue)… Read more »

Cardamom (Elettaria cardamomum) essential oil significantly inhibits vascular cell adhesion molecule 1 and impacts genome-wide gene expression in human dermal fibroblasts

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Han X, Parker TL Cogent Medicine, 2017 ABSTRACT: Cardamom (Elettaria cardamomum) essential oil (CEO) is popular in skin care, although no studies have reported its biological activity in human skin cells. We studied its effect on 17 protein biomarkers closely related to inflammation, immune responses, and tissue remodeling using a dermal fibroblast cell culture system… Read more »

Essential oils and their constituents as anticancer agents: a mechanistic view

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Gautam N, Mantha AK, Mittal S BioMed Research International, 2014 ABSTRACT: Exploring natural plant products as an option to find new chemical entities as anticancer agents is one of the fastest growing areas of research. Recently, in the last decade, essential oils (EOs) have been under study for their use in cancer therapy and the… Read more »

Repeated-doses and reproductive toxicity studies of the monoterpene 1,8-cineole (eucalyptol) in Wistar rats

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Caldas GF, Limeira MM, Araújo AV, Albuquerque GS, Silva-Neto JD, Silva TG, Costa-Silva JH, Menezes IR, Costa JG, Wanderley AG Food and Chemical Toxicology, 2016 ABSTRACT: 1,8-cineole (eucalyptol) is widely used as an excipient in the pharmaceutical industry and as a food flavoring agent, thus providing significant potential for human exposure to the compound. We… Read more »