Venzon L, Mariano LNB, Somensi LB, Boeing T, de Souza P, Wagner TM, Andrade SF, Nesello LAN, da Silva LM Biomedicine & Pharmacotherapy, 2018 ABSTRACT: Cymbopogon citratus, popularly known as lemongrass, is used for the treatment of gastric, nervous and hypertensive disorders, in addition to its use in the food and pharmaceutical industries. This study… Read more »
Geraniol
- Backbone: Monoterpene
- Functional Group: Alcohol
Cytotoxic and genotoxic potential of geraniol in peripheral blood mononuclear cells and human hepatoma cell line (HepG2)
Queiroz TB, Santos GF, Ventura SC, Hiruma-Lima CA, Gaivão IOM, Maistro EL Genetics and Molecular Research, 2017 ABSTRACT: Geraniol is an acyclic monoterpene alcohol present in the essential oil of many aromatic plants and is one of the most frequently used molecules by the flavor and fragrance industries. The literature also reports its therapeutic potential, highlighting itself… Read more »
Role of geraniol against lead acetate-mediated hepatic damage and their interaction with liver carboxylesterase activity in rats
Ozkaya A, Sahin Z, Kuzu M, Saglam YS, Ozkaraca M, Uckun M, Yologlu E, Comakli V, Demirdag R, Yologlu S Archives of Physiology and Biochemistry, 2017 ABSTRACT: In this study, the effect of geraniol (50 mg/kg for 30 d), a natural antioxidant and repellent/antifeedant monoterpene, in a rat model of lead acetate-induced (500 ppm for 30 d) liver damage was evaluated…. Read more »
Rosa damascena Mill. Essential Oil Has Protective Effect Against Testicular Damage in Diabetic Rats
Hamedi S, Shomali T, Haghighat A Journal of Dietary Supplements, 2017 ABSTRACT: This study investigates the protective effect of Rosa damascena essential oil on diabetes-induced testicular damage in rats. Thirty-six male Wistar rats were randomly divided into 6 equal groups: Group I: negative control (no treatment); Group II: positive control (diabetic by alloxan injection); Groups III-VI that… Read more »
Antifungal mechanism of the combination of Cinnamomum verum and Pelargonium graveolens essential oils with fluconazole against pathogenic Candida strains
Essid R, Hammami M, Gharbi D, Karkouch I, Hamouda TB, Elkahoui S, Limam F, Tabbene O Applied Microbiology and Biotechnology, 2017 ABSTRACT: The present study aimed to investigate the anti-Candida activity of ten essential oils (EOs) and to evaluate their potential synergism with conventional drugs. The effect on secreted aspartic protease (SAP) activity and the mechanism of action were also explored. The… Read more »
Antioxidant and antibacterial activities of Pelargonium asperum and Ormenis mixta essential oils and their synergistic antibacterial effect
Ouedrhiri W, Balouiri M, Bouhdid S, Harki EH, Moja S, Greche Environmental Science and Pollution Research International, 2017 ABSTRACT: In this work, the chemical composition, the antioxidant, and the antibacterial activities of two Moroccan essential oils less studied, extracted from Pelargonium asperum and Ormenis mixta, were investigated. According to the gas chromatography coupled to mass spectrometry analysis, citronellol (25.07%), citronellyl… Read more »
Negative inotropism of terpenes on guinea pig left atrium: structure-activity relationships
Vasconcelos CML, Oliveira ISN, Santos JNA, Souza AA, Menezes-Filho JER, Silva Neto JA, Lima TC, de Sousa DP Natural Product Research, 2017 ABSTRACT: The aim of this work was to evaluate the pharmacological effect of seven structurally related terpenes on the contractility of cardiac muscle. The effect of terpenes was studied on isolated electrically driven guinea pig left atrium. From concentration-response curves… Read more »
Polymer nanoparticles containing essential oils: new options for mosquito control
Werdin González JO, Jesser EN, Yeguerman CA, Ferrero AA, Fernández Band B Environmental Science and Pollution Research, 2017 ABSTRACT: Mosquitoes (Diptera: Culicidae) are vectors of important parasites and pathogens causing death, poverty and social disability worldwide. The overuse of synthetic insecticides to control mosquito vectors lead to resistance, adverse environmental effects and high operational costs…. Read more »
Lemongrass (Cymbopogon flexuosus) essential oil demonstrated anti-inflammatory effect in pre-inflamed human dermal fibroblasts
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: Lemongrass (Cymbopogon flexuosus) essential oil (LEO), which has citral as its main component, has exhibited anti-inflammatory effect in both animal and human cells. In this study, we evaluated the anti-inflammatory activity of a commercially available LEO in pre-inflamed human dermal fibroblasts. We first studied the impact of… Read more »
Bergamot (Citrus bergamia) Essential Oil Inhalation Improves Positive Feelings in the Waiting Room of a Mental Health Treatment Center: A Pilot Study
Han X, Gibson J, Eggett DL, Parker TL Phytotherapy Research, 2017 ABSTRACT: Mental health issues have been increasingly recognized as public health problems globally. Their burden is projected to increase over the next several decades. Additional therapies for mental problems are in urgent need worldwide due to the limitations and costs of existing healthcare approaches…. Read more »