Immune System

This system includes the lymph nodes, white blood cells, lymphatic vessels, thymus gland, bone marrow, spleen and leukocytes. Common disorders include anything with bacterial, viral or fungal origins, leukemia, allergic reactions and autoimmune diseases like lupus or rheumatoid arthritis.

Cardamom (Elettaria cardamomum) essential oil significantly inhibits vascular cell adhesion molecule 1 and impacts genome-wide gene expression in human dermal fibroblasts

Han X, Parker TL Cogent Medicine, 2017 ABSTRACT: Cardamom (Elettaria cardamomum) essential oil (CEO) is popular in skin care, although no studies have reported its biological activity in human skin cells. We studied its effect on 17 protein biomarkers closely related to inflammation, immune responses, and tissue remodeling using a dermal fibroblast cell culture system… Read more »

Arborvitae (Thuja plicata) essential oil significantly inhibited critical inflammation- and tissue remodeling-related proteins and genes in human dermal fibroblasts

Han X, Parker TL Biochimie Open, 2017 ABSTRACT: Arborvitae (Thuja plicata) essential oil (AEO) is becoming increasingly popular in skincare, although its biological activity in human skin cells has not been investigated. Therefore, we sought to study AEO’s effect on 17 important protein biomarkers that are closely related to inflammation and tissue remodeling by using… Read more »

Anti-inflammatory activity of clove (Eugenia caryophyllata) essential oil in human dermal fibroblasts

Han X, Parker TL Pharmaceutical Biology, 2017 CONTEXT: Clove (Eugenia caryophyllata Thunb. [Myrtaceae]) essential oil (CEO) has been shown to possess antimicrobial, antifungal, antiviral, antioxidant, anti-inflammatory and anticancer properties. However, few studies have focused on its topical use. OBJECTIVE: We investigated the biological activity of a commercially available CEO in a human skin disease model…. Read more »

Essential oils and their constituents as anticancer agents: a mechanistic view

Gautam N, Mantha AK, Mittal S BioMed Research International, 2014 ABSTRACT: Exploring natural plant products as an option to find new chemical entities as anticancer agents is one of the fastest growing areas of research. Recently, in the last decade, essential oils (EOs) have been under study for their use in cancer therapy and the… Read more »

Antitumor phenylpropanoids found in essential oils

Carvalho AA, Andrade LN, de Sousa ÉB, de Sousa DP Biomed Research International, 2015  ABSTRACT: The search for new bioactive substances with anticancer activity and the understanding of their mechanisms of action are high-priorities in the research effort toward more effective treatments for cancer. The phenylpropanoids are natural products found in many aromatic and medicinal… Read more »

The Effect of Citrus Essential Oils and Their Constituents on Growth of Xanthomonas citri subsp. citri

Mirzaei-Najafgholi H, Tarighi S, Golmohammadi M, Taheri P Molecules, 2017 ABSTRACT: Citrus bacterial canker (CBC) caused by Xanthomonas citri subsp. citri (Xcc), is the most devastating of the citrus diseases worldwide. During our study, we found that Essential oils (EOs) of some citrus cultivars are effective on Xcc. Therefore, it prompted us to determine the… Read more »

Medicinal and biological values of Callistemon viminalis extracts: History, current situation and prospects

Salem MZM, El-Hefny M, Nasser RA, Ali HM, El-Shanhorey NA, Elansary HO Asian Pacific journal of trpical medicine, 2017 ABSTRACT: Callistemon viminalis (C. viminalis) is a plant that has been reported to have various medicinal values such as antibacterial, antifungal, antioxidant activities and other pharmaceutical and insecticidal properties. This review covers the potentials, applications and properties… Read more »

Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral

Adukwu EC, Bowles M, Edwards-Jones V, Bone H Applied microbiology and biotechnology, 2016 ABSTRACT: The aim of this study was to determine the antimicrobial effects of lemongrass essential oil (C. flexuosus) and to determine cytotoxic effects of both test compounds on human dermal fibroblasts. Antimicrobial susceptibility screening was carried out using the disk diffusion method…. Read more »

The influence of environmentally friendly pesticide – Eucalyptol – alone and in combination with terpinen-4-ol – on model bacterial membranes

Hąc-Wydro K, Szydło K Colloids and surfaces. B, Biointerfaces, 2016 ABSTRACT: Eucalyptus oil is known from antimicrobial properties and due to natural origin and low toxicity it can be applied as a green pesticide. This plant extract is a mixture of compounds among which Eucalyptol prevails strongly over the number of minor components including terpinen-4-ol…. Read more »

Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol

Khosravi AR, Erle DJ PloS one, 2016 ABSTRACT: Chitin is produced in large amounts by fungi, insects, and other organisms and has been implicated in the pathogenesis of asthma. Airway epithelial cells are in direct contact with environmental particles and serve as the first line of defense against inhaled allergens and pathogens. The potential contributions… Read more »