Linalool

  • Backbone: Monoterpene
  • Functional Group: Alcohol

Cananga odorata essential oil reverses the anxiety induced by 1-(3-chlorophenyl) piperazine through regulating the MAPK pathway and serotonin system in mice

Zhang N, Zhang L, Feng L, Yao L Journal of Ethnopharmacology, 2018 ABSTRACT: ETHNOPHARMACOLOGICAL RELEVANCE: Cananga odorata essential oil, known as ylang-ylang essential oil (YYO), was commonly used in the aromatherapy for relaxation and mood adjusting use. In our previous study, YYO played anxiolytic effects on the mice in several behavioral tests that based on… Read more »

Neuropharmacological Properties of the Essential Oil of Bergamot for the Clinical Management of Pain-Related BPSDs

Scuteri D, Rombola L, Tridico L, Mizoguchi H, Watanabe C, Sakurada T, Sakurada S, Corasaniti MT, Bagetta G, Morrone LA Current Medicinal Chemistry, 2018 ABSTRACT: BACKGROUND: Alzheimer’s Disease (AD) accounts for approximately 50% of all cases of dementia and, in spite of the great effort for the development of disease-modifying drugs, a definitive treatment of… Read more »

Cinnamomum zeylanicum bark essential oil induces cell wall remodelling and spindle defects in Candida albicans

Shahina Z, El-Ganiny AM, Minion J, Whiteway M, Sultana T, Dahms TES Fungal Biology and Biotechnology, 2018 ABSTRACT: BACKGROUND: Cinnamon (Cinnamomum zeylanicum) bark extract exhibits potent inhibitory activity against Candida albicans but the antifungal mechanisms of this essential oil remain largely unexplored. RESULTS: We analyzed the impact of cinnamon bark oil on C. albicans RSY150,… Read more »

Chemical composition analysis and in vitro biological activities of ten essential oils in human skin cells

Han X, Beaumont C, Stevens N Biochimie Open, 2017 ABSTRACT: Research on the biological effects of essential oils on human skin cells is scarce. In the current study, we primarily explored the biological activities of 10 essential oils (nine single and one blend) in a pre-inflamed human dermal fibroblast system that simulated chronic inflammation. We… Read more »

Selected terpenes from leaves of Ocimum basilicum L. induce hemoglobin accumulation in human K562 cells

Giordana F, Nicola M, Valentina C, Torricelli P, Beninati S, Tagliati F, Mischiati C Fitoterapia, 2018 ABSTRACT: Re-expression of fetal hemoglobin (HbF) was proposed as a possible therapeutic strategy for β-haemoglobinopathies. Although several inducers of HbF were tested in clinical trials, only hydroxyurea (HU) received FDA approval. Despite it produced adequate HbF levels only in… Read more »

Anti-inflammatory effect of cinnamaldehyde and linalool from the leaf essential oil of Cinnamomum osmophloeum Kanehira in endotoxin-induced mice

Lee SC, Wang SY, Li CC, Liu CT Journal of Food and Drug Analysis, 2018 ABSTRACT: Cinnamomum osmophloeum Kanehira is a Taiwan native plant that belongs to genus Cinnamomum and is also known as pseudocinnamomum or indigenous cinnamon. Its leaf is traditionally used by local people in cooking and as folk therapy. We previously demonstrated… Read more »

Neurotoxic Effects of Linalool and β-Pinene on Tribolium castaneum Herbst.

Pajaro-Castro N, Caballero-Gallardo K, Olivero-Verbel J Molecules, 2017 ABSTRACT: Effective, ethical pest control requires the use of chemicals that are highly specific, safe, and ecofriendly. Linalool and β-pinene occur naturally as major constituents of the essential oils of many plant species distributed throughout the world, and thus meet these requirements. These monoterpenes were tested as repellents against Tribolium… Read more »

Antibacterial activity of essential oil from lavender (Lavandula angustifolia) against pet turtle-borne pathogenic bacteria

Hossain S, Heo H, De Silva BCJ, Wimalasena SHMP, Pathirana HNKS, Heo GJ Lab Animal Research, 2017 ABSTRACT: Pet turtles are well-known to harbor an array of bacterial pathogens which can cause zoonotic infections in humans as well as opportunistic infections in the turtles itself. Essential oils are the natural plant extracts which have been traditionally used… Read more »

Antimicrobial and synergistic activity of essential oils of Aloysia triphylla and Lippia alba against Aeromonas spp

de Souza RC, da Costa MM, Baldisserotto B, Heinzmann BM, Schmidt D, Caron BO, Copatti CE Microbial Pathogenesis, 2017 ABSTRACT: The objective of this study was to identify and quantify the chemical constituents, as well as the antimicrobial, antibiofilm and synergistic activity with florfenicol of essential oils of Aloysia triphylla (EOAT) and Lippia alba (EOLA) against Aeromonas… Read more »

Linalool-rich essential oils from the Amazon display antidepressant-type effect in rodents

Dos Santos ÉRQ, Maia CSF, Fontes Junior EA, Melo AS, Pinheiro BG, Maia JGS Journal of Ethnopharmacology, 2017 ETHNOPHARMACOLOGICAL RELEVANCE: The essential oils of the leaves of Aniba rosaeodora (pau-rosa), Aniba parviflora (macacaporanga) and Aeollanthus suaveolens (catinga-de-mulata), rich in linalool, are used in the traditional medicine of the Brazilian Amazon for its effects on the central nervous… Read more »