da Silva RER, de Morais LP, Silva AA, Bastos CMS, Pereira-Gonçalves Á, Kerntopf MR, Menezes IRA, Leal-Cardoso JH, Barbosa R Biomedicine and Pharmacotherapy, 2018 ABSTRACT: The Lippia alba (Mill.) N.E. Brown (Verbenaceae) species popularly known as lemon balm has sedative, analgesic and spasmolytic properties. This study aimed to evaluate the vasorelaxant effect of the L…. Read more »
Neral
- Backbone: Monoterpene
- Functional Group: Aldehyde
Transcriptomic approach and membrane fatty acid analysis to study the response mechanisms of Escherichia coli to thyme essential oil, carvacrol, 2-(E)-hexanal and citral exposure
Siroli L, Braschi G, De jong A, Kok J, Patrignani F, Lanciotti R Journal of Applied Microbiology, 2018 ABSTRACT: AIMS: The application of essential oils (EOs) and their components as food preservatives is promising but requires a deeper understanding of their mechanisms of action. This study aims to evaluate the effects of thyme EO, carvacrol,… Read more »
Essential oil from Cymbopogon flexuosus as the potential inhibitor for HSP90
Gaonkar R, Shiralgi Y, Lakkappa DB, Hegde G Toxicology Reports, 2018 ABSTRACT: The essential oil of Cymbopogon flexuosus or lemongrass oil (LO) is reported to have antibacterial, antifungal and anticancerous effects. HSP90 is one of the major chaperones responsible for the proper folding of cancer proteins. In this paper we show that the essential oil… Read more »
Antihyperlipidemic and anti-hyperglycemic effects of Cymbopogon jwarancusa in high-fat high-sugar diet model
Khan SJ, Afroz S, Khan RA Pakistan Journal of Pharmaceutical Sciences, 2018 ABSTRACT: Hyperlipidemia is the root cause for development of atherosclerosis, coronary heart disease, diabetes mellitus, obesity, hypertension and cerebral palsy. Cymbopogon jwarancusa is an aromatic grass (Rusha grass, khavi grass) belonging to family Poaceaea. C. jwarancusa essential oil is famous for its use… Read more »
Nanoemulsions containing Cymbopogon flexuosus essential oil: Development, characterization, stability study and evaluation of antimicrobial and antibiofilm activities
da Silva Gündel S, de Souza ME, Quatrin PM, Klein B, Wagner R, Gündel A, Vaucher RA, Santos RCV, Ourique AF Microbial Pathogenesis, 2018 ABSTRACT: The increase of microbial resistance generates the search for new substances with antimicrobial potential. The essential oil of Cymbopogon flexuosus (Lemongrass) stands out in the literature for its antimicrobial, insecticide… Read more »
Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents
Maruoka T, Kitanaka A, Kubota Y, Yamaoka G, Kameda T, Imataki O, Dobashi H, Bandoh S, Kadowaki N, Tanaka T International Journal of Oncology, 2018 ABSTRACT: Small-cell lung cancer (SCLC) is intractable due to its high propensity for relapse. Novel agents are thus needed for SCLC treatment. Lemongrass essential oil (LG-EO) and its major constituent,… Read more »
Cymbopogon citratus and Cymbopogon giganteus essential oils have cytotoxic effects on tumor cell cultures. Identification of citral as a new putative anti-proliferative molecule
Bayala B, Bassole IHN, Maqdasy S, Baron S, Simpore J, Lobaccaro JA Biochimie, 2018 ABSTRACT: Cymbopogon species are used as traditional remedies in Burkina Faso for treating several diseases. We aimed to study the effects of their essential oils on cancer cell lines. For that purpose, Cymbopogon citratus (DC.) Stapf. and Cymbopogon giganteus Chiov. were… Read more »
Lemongrass (Cymbopogon flexuosus) essential oil demonstrated anti-inflammatory effect in pre-inflamed human dermal fibroblasts
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: Lemongrass (Cymbopogon flexuosus) essential oil (LEO), which has citral as its main component, has exhibited anti-inflammatory effect in both animal and human cells. In this study, we evaluated the anti-inflammatory activity of a commercially available LEO in pre-inflamed human dermal fibroblasts. We first studied the impact of… Read more »
Antifungal and Anti-Biofilm Activity of Essential Oil Active Components against Cryptococcus neoformans and Cryptococcus laurentii
Kumari P, Mishra R, Arora N, Chatrath A, Gangwar R, Roy P, Prasad R Frontiers in Microbiology, 2017 ABSTRACT: Cryptococcosis is an emerging and recalcitrant systemic infection occurring in immunocompromised patients. This invasive fungal infection is difficult to treat due to the ability of Cryptococcus neoformans and Cryptococcus laurentii to form biofilms resistant to standard antifungal treatment…. Read more »
Antimicrobial and synergistic activity of essential oils of Aloysia triphylla and Lippia alba against Aeromonas spp
de Souza RC, da Costa MM, Baldisserotto B, Heinzmann BM, Schmidt D, Caron BO, Copatti CE Microbial Pathogenesis, 2017 ABSTRACT: The objective of this study was to identify and quantify the chemical constituents, as well as the antimicrobial, antibiofilm and synergistic activity with florfenicol of essential oils of Aloysia triphylla (EOAT) and Lippia alba (EOLA) against Aeromonas… Read more »