Garlet QI, da Costa Pires L, Milanesi LH, Marafiga JR, Baldisserotto B, de Mello CF, Heinzmann BM Toxicology and Applied Pharmacology, 2017 ABSTRACT: (+)-Dehydrofukinone (DHF), isolated from Nectandra grandiflora (Lauraceae) essential oil, induces sedation and anesthesia by modulation of GABAa receptors. However, no study has addressed whether DHF modulates other cellular events involved in the control of cellular excitability, such as seizure… Read more »
Nervous System
This system includes the brain, spinal cord, sensory receptors and peripheral nerves. Disorders include strokes, dementia, Alzheimer’s, Huntington’s, Parkinson’s, ADHD, epilepsy, anxiety disorders, mood disorders and stress.
Chemical Composition and Antimigraine Activity of Essential Oil of Angelicae dahuricae Radix
Sun J, Li H, Sun J, Liu H, Chen J, Wang C Journal of Medicinal Food, 2017 ABSTRACT: The aim of this study was to explore the chemical composition and the effect of essential oil of Angelicae dahuricae radix on a nitroglycerin (NTG)-induced rat model of migraine. The CO2 supercritical fluid extraction method was optimized for the extraction of essential oil of A. dahuricae radix… Read more »
Evidence for the involvement of the GABAergic, but not serotonergic transmission in the anxiolytic-like effect of bisabolol in the mouse elevated plus maze
Tabari MA, Tehrani MAB Naunyn-Schmiedeberg’s Archives of Pharmacology, 2017 ABSTRACT: Bisabolol (α-(-)-bisabolol) is a sesquiterpene which is a part of the essential oil of a variety of plants, but its common source is German chamomile. Several bioactivities including anti-inflammatory, anti-nociceptive, and anti-tumor effects were attributed to bisabolol. However, the neuropharmacological properties of bisabolol have not yet been reported…. Read more »
Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities
Demirci B, Yusufoglu HS, Tabanca N, Temel HE, Bernier UR, Agramonte NM, Alqasoumi SI, Al-Rehaily AJ, Başer KHC, Demirci F Saudi Pharmaceutical Journal, 2017 ABSTRACT: The essential oil (EO) of the aerial parts of Rhanterium epapposum Oliv. (Asteraceae), was obtained by hydrodistillation. The oil was subsequently analyzed by both GC-FID and GC-MS, simultaneously. Forty-five components representing 99.2% of the oil composition were identified. The most abundant compounds were… Read more »
Metabolic Products of Linalool and Modulation of GABAA Receptors
Milanos S, Elsharif SA, Janzen D, Buettner A, Villmann C Frontiers in Chemistry, 2017 ABSTRACT: Terpenoids are major subcomponents in aroma substances which harbor sedative physiological potential. We have demonstrated that various monoterpenoids such as the acyclic linalool enhance GABAergic currents in an allosteric manner in vitro upon overexpression of inhibitory α1β2 GABAA receptors in various expression systems. However, in plants or humans, i.e.,… Read more »
Neuroprotective Effects of β-Caryophyllene against Dopaminergic Neuron Injury in a Murine Model of Parkinson’s Disease Induced by MPTP
Viveros-Paredes JM, González-Castañeda RE, Gertsch J, Chaparro-Huerta V, López-Roa RI, Vázquez-Valls E, Beas-Zarate C, Camins-Espuny A, Flores-Soto ME Pharmaceuticals (Basel, Switzerland), 2017 ABSTRACT: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders and is characterized by the loss of dopaminergic neurons in the substantia nigra (SN). Although the causes of PD are not understood, evidence suggests that its pathogenesis is associated… Read more »
Aromatherapy Massage for Neuropathic Pain and Quality of Life in Diabetic Patients
Gok Metin Z, Arikan Donmez A, Izgu N, Ozdemir L, Arslan IE Journal of Nursing Scholarship, 2017 ABSTRACT: PURPOSE: This study aimed to examine the effects of aromatherapy massage on neuropathic pain severity and quality of life (QoL) in patients suffering from painful diabetic neuropathy. DESIGN AND METHODS: This open-label randomized controlled clinical study was conducted in a university hospital… Read more »
Aromatherapy and Essential Oils (PDQ®): Health Professional Version
PDQ Integrative, Alternative, and Complementary Therapies Editorial Board PDQ Cancer Information Summaries, 2017 EXCERPT: This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the use of aromatherapy and essential oils in the treatment of people with cancer. It is intended as a resource to inform and assist clinicians who care for cancer… Read more »
The Effect of Aromatherapy on Insomnia and Other Common Symptoms Among Patients With Acute Leukemia
Blackburn L, Achor S, Allen B, Bauchmire N, Dunnington D, Klisovic RB, Naber SJ, Roblee K, Samczak A, Tomlinson-Pinkham K, Chipps E Oncology Nursing Forum, 2017 ABSTRACT: PURPOSE/OBJECTIVES: To determine if the use of aromatherapy improves insomnia and other common symptoms in hospitalized patients with newly diagnosed acute leukemia. DESIGN: A randomized, crossover, washout trial. SETTING: An inpatient acute leukemia unit at the Arthur G…. Read more »
A systematic review of the effect of inhaled essential oils on sleep
Lillehei AS, Halcon LL Journal of Alternative and Complementary Medicine, 2014 ABSTRACT: OBJECTIVE: Sleep disturbances are recognized as an important health and public health problem that affects physical, mental, and emotional health and well-being. Inhalation of essential oils may be a safe alternative to pharmaceutical interventions for mild to moderate sleep disturbances. Quantitative human studies… Read more »