Lee J, Lee SH Current Developments in Nutrition, 2019 ABSTRACT: OBJECTIVES: Patchouli alcohol is one of the abundant compounds isolated from essential oil of Pogostemon cablin and shows anti-inflammatory, anti-obese and anti-cancer activities. The current study was designed to investigate if treatment of patchouli alcohol exhibits tumor suppressive activity in colon cancer mouse model and… Read more »
- Botanical Name: Pogostemon cablin
- Alternative Names: Patchouly
- Botanical Family: Lamiaceae
- Primary Constituent: Patchouli alcohol
- Other Main Constituents: Alpha-bulnesene, Alpha-guaiene
- Distillation Method: Steam Distillation
- Plant Part: Leaf
The in vitro antimicrobial evaluation of commercially essential oils and their combinations against acne
Orchard A, van Vuuren SF, Viljoen A, Kamatou G International Journal of Cosmetic Science, 2018 ABSTRACT: OBJECTIVE: The study investigated the efficacy of commercial essential oil combinations against the two pathogens responsible for acne with the aim to identify synergy and favourable oils to possibly use in a blend. METHODS AND MATERIALS: Antimicrobial activity was… Read more »
Effects of patchouli and cinnamon essential oils on biofilm and hyphae formation by Candida species
Farisa Banu S, Rubini D, Shanmugavelan P, Murugan R, Gowrishankar S, Karutha Pandian S, Nithyanand P Journal de Mycologie Medicale, 2018 ABSTRACT: The prevalence and fatality rates with biofilm-associated candidal infections have remained a challenge to the medical fraternity despite major advances in the field of antifungal therapy. Traditionally, essential oils (EOs) from the aromatic… Read more »
Chemical composition analysis and in vitro biological activities of ten essential oils in human skin cells
Han X, Beaumont C, Stevens N Biochimie Open, 2017 ABSTRACT: Research on the biological effects of essential oils on human skin cells is scarce. In the current study, we primarily explored the biological activities of 10 essential oils (nine single and one blend) in a pre-inflamed human dermal fibroblast system that simulated chronic inflammation. We… Read more »
Patchouli oil ameliorates acute colitis: A targeted metabolite analysis of 2,4,6-trinitrobenzenesulfonic acid-induced rats
Yu X, Yang G, Jiang H, Lin S, Liu Y, Zhang X, Zeng H, Su Z, Huang S, Shen L, Zhang X Experimental and Therapeutic Medicine, 2017 ABSTRACT: The incidence of inflammatory bowel disease (IBD), characterized by chronic, relapsing intestinal inflammation, has continually increased in recent years. A previous study by our group identified five… Read more »
Anti-nociceptive effect of patchouli alcohol: Involving attenuation of cyclooxygenase 2 and modulation of mu-opioid receptor
Yu X, Wang XP, Yan XJ, Jiang JF, Lei F, Xing DM, Guo YY, Du LJ Chinese Journal of Integrated Medicine, 2017 OBJECTIVE: To explore the anti-nociceptive effect of patchouli alcohol (PA), the essential oil isolated from Pogostemon cablin (Blanco) Bent, and determine the mechanism in molecular levels. METHODS: The acetic acid-induced writhing test and formalin-induced plantar… Read more »
β-Patchoulene from patchouli oil protects against LPS-induced acute lung injury via suppressing NF-κB and activating Nrf2 pathways
Chen XY, Dou YX, Luo DD, Zhang ZB, Li CL, Zeng HF, Su ZR, Xie JH, Lai XP, Li YC International Immunopharmacology, 2017 ABSTRACT: β-Patchoulene (β-PAE), a tricyclic sesquiterpene isolated from the essential oil of the leaves and stems of Pogostemon cablin (Blanco) Benth., has been reported to have potent anti-inflammatory activity. The aim of this study was to evaluate the potential protective effect of β-PAE… Read more »
Aromatherapy and Essential Oils (PDQ®): Health Professional Version
PDQ Integrative, Alternative, and Complementary Therapies Editorial Board PDQ Cancer Information Summaries, 2017 EXCERPT: This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the use of aromatherapy and essential oils in the treatment of people with cancer. It is intended as a resource to inform and assist clinicians who care for cancer… Read more »
The in vitro Antimicrobial Activity and Chemometric Modelling of 59 Commercial Essential Oils against Pathogens of Dermatological Relevance.
Orchard A, Sandasi M, Kamatou G, Viljoen A, van Vuuren S Chemistry & Biodiversity, 2017 ABSTRACT: This study reports on the inhibitory concentration of 59 commercial essential oils recommended for dermatological conditions, and identifies putative compounds responsible for antimicrobial activity. Essential oils were investigated for antimicrobial activity using minimum inhibitory concentration assays. Ten essential oils… Read more »
Chemical composition analysis and in vitro biological activities of ten essential oils in human skin cells
Han X, Beaumont C, Stevens N, Parker TL Biochimie Open, 2017 ABSTRACT: Research on the biological effects of essential oils on human skin cells is scarce. In the current study, we primarily explored the biological activities of 10 essential oils (nine single and one blend) in a pre-inflamed human dermal fibroblast system that simulated chronic… Read more »