Anti-edematogenic and anti-inflammatory activity of the essential oil from Croton rhamnifolioides leaves and its major constituent 1,8-cineole (eucalyptol)

Martins AOBPB, Rodrigues LB, Cesário FRAS, de Oliveira MRC, Tintino CDM, Castro FFE, Alcântara IS, Fernandes MNM, de Albuquerque TR, da Silva MSA, de Sousa Araújo AA, Júniur LJQ, da Costa JGM, de Menezes IRA, Wanderley AG Biomedicine & Pharmacotherapy, 2017 ABSTRACT: The species Croton rhamnifolioides, belonging to the Croton genus, is known in ethnomedicine… Read more »

Evaluation of the Constituents of Vetiver Oil Against Anopheles minimus (Diptera: Culicidae), a Malaria Vector in Thailand

Tisgratog R, Sukkanon C, Grieco JP, Sanguanpong U, Chauhan KR, Coats JR, Chareonviriyaphap T Journal of Medical Entomology, 2017 ABSTRACT: The development of resistance by mosquitoes to current synthetic compounds has resulted in reduced effectiveness of prevention and control methods worldwide. An alternative nonchemical based control tools are needed to be evaluated particularly plant-derived essential oils…. Read more »

Combined Toxicity of Three Essential Oils Against Aedes aegypti (Diptera: Culicidae) Larvae

Muturi EJ, Ramirez JL, Doll KM, Bowman MJ Journal of Medical Entomology, 2017 ABSTRACT: Essential oils are potential alternatives to synthetic insecticides because they have low mammalian toxicity, degrade rapidly in the environment, and possess complex mixtures of bioactive constituents with multi-modal activity against the target insect populations. Twenty-one essential oils were initially screened for their toxicity against… Read more »

Eugenol inhibits oxidative phosphorylation and fatty acid oxidation via downregulation of c-Myc/PGC-1β/ERRα signaling pathway in MCF10A-ras cells

Yan X, Zhang G, Bie F, Lv Y, Ma Y, Ma M, Wang Y, Hao X, Yuan N, Jiang X Scientific Republic, 2017 ABSTRACT: Alteration in cellular energy metabolism plays a critical role in the development and progression of cancer. Targeting metabolic pathways for cancer treatment has been investigated as potential preventive or therapeutic methods…. Read more »

Chemical composition of the essential oils isolated from peel of three citrus species and their mosquitocidal activity against Culex pipiens

Badawy MEI, Taktak NEM, El-Aswad AF Natural Product Research, 2017 ABSTRACT: Three essential oils (EOs) were isolated from the peel of citrus fruits Citrus reticulata L., Citrus reticulata chinase Blanco and Citrus sinensis (L.) Osbeck (Family: Rutaceae) and evaluated against Culex pipiens L.1758 (Family: Culicidae). Chemical composition indicated that the EOs were rich in essential phytochemicals including… Read more »

Perspectives on medicinal properties of natural phenolic monoterpenoids and their hybrids

Rajput JD, Bagul SD, Pete UD, Zade CM, Padhye SB, Bendre RS Molecular Diversity, 2017 ABSTRACT: Carvacrol, thymol and eugenol belong to a class of naturally presenting phenols with a ten-carbon unit, which are present in essential oils of many plants. These versatile molecules are incorporated as useful ingredients in many food products and find applications in… Read more »

Carvacrol-rich oregano oil and thymol-rich thyme red oil inhibit biofilm formation and the virulence of uropathogenic Escherichia coli

Lee JH, Kim YG, Lee J Journal of Applied Microbiology, 2017 AIMS: Urinary tract infections are caused primarily by uropathogenic Escherichia coli (UPEC), and indwelling catheters are usually colonized by UPEC biofilms tolerant to common antibiotics. Hence, UPEC biofilms pose a substantial challenge, and there is an urgent need for effective control strategies. METHODS AND… Read more »

Four terpene synthases contribute to the generation of chemotypes in tea tree (Melaleuca alternifolia)

Padovan A, Keszei A, Hassan Y, Krause ST, Köllner TG, Degenhardt J, Gershenzon J, Külheim C, Foley WJ BMC Plant Biology, 2017 BACKGROUND: Terpene rich leaves are a characteristic of Myrtaceae. There is significant qualitative variation in the terpene profile of plants within a single species, which is observable as “chemotypes”. Understanding the molecular basis… Read more »

Cytotoxic and genotoxic potential of geraniol in peripheral blood mononuclear cells and human hepatoma cell line (HepG2)

Queiroz TB, Santos GF, Ventura SC, Hiruma-Lima CA, Gaivão IOM, Maistro EL Genetics and Molecular Research, 2017 ABSTRACT: Geraniol is an acyclic monoterpene alcohol present in the essential oil of many aromatic plants and is one of the most frequently used molecules by the flavor and fragrance industries. The literature also reports its therapeutic potential, highlighting itself… Read more »