Emílio-Silva MT, Mota CMD, Hiruma-Lima CA, Antunes-Rodrigues J, Cárnio EC, Branco LGS Inflammation, 2017 ABSTRACT: Citral is a mixture of the two monoterpenoid isomers (neral and geranial) widely used as a health-promoting food additive safe for human and animal (approved by the US Food and Drug Administration). In vitro studies have reported on the capability of citral to reduce inflammation. Here, we report antipyretic effects… Read more »
Antiparasitic activity of nerolidol in a mouse model of schistosomiasis
Silva MP, de Oliveira RN, Mengarda AC, Roquini DB, Alegretti SM, Salvadori MC, Teixeira FS, de Sousa DP, Pinto PLS, de Moraes J International Journal of Antimicrobial Agents, 2017 ABSTRACT: Schistosomiasis is a major public health problem worldwide, especially in poor communities. Since praziquantel is currently the only drug available to treat schistosomiasis, there is an urgent need to identify new antischistosomal drugs. Nerolidol… Read more »
Aromatherapy and Essential Oils (PDQ®): Health Professional Version
PDQ Integrative, Alternative, and Complementary Therapies Editorial Board PDQ Cancer Information Summaries, 2017 EXCERPT: This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the use of aromatherapy and essential oils in the treatment of people with cancer. It is intended as a resource to inform and assist clinicians who care for cancer… Read more »
Negative inotropism of terpenes on guinea pig left atrium: structure-activity relationships
Vasconcelos CML, Oliveira ISN, Santos JNA, Souza AA, Menezes-Filho JER, Silva Neto JA, Lima TC, de Sousa DP Natural Product Research, 2017 ABSTRACT: The aim of this work was to evaluate the pharmacological effect of seven structurally related terpenes on the contractility of cardiac muscle. The effect of terpenes was studied on isolated electrically driven guinea pig left atrium. From concentration-response curves… Read more »
The Effect of Aromatherapy on Insomnia and Other Common Symptoms Among Patients With Acute Leukemia
Blackburn L, Achor S, Allen B, Bauchmire N, Dunnington D, Klisovic RB, Naber SJ, Roblee K, Samczak A, Tomlinson-Pinkham K, Chipps E Oncology Nursing Forum, 2017 ABSTRACT: PURPOSE/OBJECTIVES: To determine if the use of aromatherapy improves insomnia and other common symptoms in hospitalized patients with newly diagnosed acute leukemia. DESIGN: A randomized, crossover, washout trial. SETTING: An inpatient acute leukemia unit at the Arthur G…. Read more »
Studies on the Behavior of Eucalyptol and Terpinen-4-ol – Natural Food Additives and Ecological Pesticides – in Model Lipid Membranes
Hąc-Wydro K, Flasiński M, Broniatowski M, Sołtys M Langmuir, 2017 ABSTRACT: Effective application of the essential oils requires detailed exploration of their mechanism of action and the origin of diverse activity of their components. In this work, the influence of eucalyptol and terpinen-4-ol on artificial membranes was studied to verify whether the differences in the activity of these compounds are… Read more »
β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway
Cheng Y, Dong Z, Liu S Pharmacology, 2014 ABSTRACT: BACKGROUND/AIMS: The activation of cannabinoid receptor 2 (CB2) has the beneficial effect of reducing neuroinflammatory response in the treatment of Alzheimer’s disease (AD) and is suggested to trigger the peroxisome proliferator-activated receptor-γ (PPARγ) pathway; agonists of both receptors improve AD. Recently, the plant metabolite β-caryophyllene was… Read more »
The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines
Ambrož M, Matoušková P, Skarka A, Zajdlová M, Žáková K, Skálová L Molecules, 2017 ABSTRACT: β-caryophyllene oxide (CAO), α-humulene (HUM), trans-nerolidol (NER) and valencene (VAL) are constituents of the essential oil of Myrica rubra (MEO), which has significant antiproliferative effect in various cancer cell lines. In the present study, we compared the antiproliferative effect of… Read more »
Global transcriptional response of Escherichia coli MG1655 cells exposed to the oxygenated monoterpenes citral and carvacrol
Chueca B, Pérez-Sáez E, Pagán R, García-Gonzalo D International Journal of Food Microbiology, 2017 ABSTRACT: DNA microarrays were used to study the mechanism of bacterial inactivation by carvacrol and citral. After 10-min treatments of Escherichia coli MG1655 cells with 100 and 50ppm of carvacrol and citral, 76 and 156 genes demonstrated significant transcriptional differences (p≤0.05),… Read more »
Effect of essential oil mouthwashes on plaque and gingivitis
Richards D Journal of Evidence-Based Dental Practice, 2017 ABSTRACT: Data sources: Medline, Embase, LILACS and Scopus database. Study selection: Studies were screened independently by three reviewers. Randomised controlled trials with a minimum of six months follow-up of daily use of essential oils-containing (EO) mouthwashes compared with placebo, flossing or cetylpyridinium chloride (CPC) as adjuncts to… Read more »