Borges RS, Lima ES, Keita H, Ferreira IM, Fernandes CP, Cruz RAS, Duarte JL, Velázquez-Moyado J, Ortiz BLS, Castro AN, Ferreira JV, da Silva Hage-Melim LI, Carvalho JCT Inflammopharmacology, 2017 ABSTRACT: We evaluate the anti-inflammatory and antialgic potency of a nanoemulsion (NEORO) containing the essential oil of Rosmarinus officinalis L. (EORO), which is composed primarily of limonene, camphor and 1,8-cineole. The EORO and NEORO were administered orally 30 min prior… Read more »
Effects of the essential oil of Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm. on healing and tissue repair after partial Achilles tenotomy in rats
Santos-Júnior L, Oliveira TVC, Cândido JF, Santana DS, Pereira RN Filho, Pereyra BBS, Gomes MZ, Lima SO, Albuquerque-Júnior RLC, Cândido Brazilian Surgical Acts, 2017 ABSTRACT: PURPOSE: To investigate the cellular response to injury, analyzing histopathologic changes associated with increased cellularity, degeneration and disorganization of collagen fibers. METHODS: Thirty wistar rats were divided in two groups after partial Achilles tenotomy: the right hind paw were… Read more »
Inactivation of Norovirus by Lemongrass Essential Oil Using a Norovirus Surrogate System
Kim YW, You HJ, Lee S, Kim B, Kim DK, Choi JB, Kim JA, Lee HJ, Joo IS, Lee JS, Kang DH, Lee G, Ko GP, Lee SJ Journal of Food Protection, 2017 ABSTRACT: This study investigated the effect of lemongrass essential oil (LGEO) on the infectivity and viral replication of norovirus. Murine norovirus 1 (MNV-1), a surrogate of human norovirus, was preincubated with LGEO and then used to infect… Read more »
The Effect of Thymoquinone on Apoptosis of SK-OV-3 Ovarian Cancer Cell by Regulation of Bcl-2 and Bax
Liu X, Dong J, Cai W, Pan Y, Li R, Li B International Journal of Gynecological Cancer, 2017 ABSTRACT: OBJECTIVE: We aim to determine how cisplatin, thymoquinone (TQ), and combination regimen can affect apoptosis of cultured SK-OV-3 cells. We also want to explore the mechanism of these influences on the cells’ apoptosis by Bcl-2 and Bax gene. METHOD/MATERIALS: Cell Counting Kit-8 assay… Read more »
Evaluation of the Health Benefits of a Multivitamin, Multimineral, Herbal, Essential Oil-Infused Supplement: A Pilot Trial
Han X, Eggett DL, Parker TL Journal of Dietary Supplements, 2017 ABSTRACT: This study was designed to quantitatively evaluate the health benefits of a multivitamin, multimineral, herbal, essential oil-infused supplement using serum biomarkers. We also qualitatively evaluated the health effects of this supplement using a survey. Sixteen participants were recruited to take the supplement as directed for two… Read more »
α-bisabolol-loaded lipid-core nanocapsules reduce lipopolysaccharide-induced pulmonary inflammation in mice
D’Almeida APL, Pacheco de Oliveira MT, de Souza ÉT, de Sá Coutinho D, Ciambarella BT, Gomes CR, Terroso T, Guterres SS, Pohlmann AR, Silva PM, Martins MA, Bernardi A International Journal of Nanomedicine, 2017 ABSTRACT: Acute respiratory distress syndrome (ARDS) is a severe clinical condition of respiratory failure due to an intense inflammatory response with different etiologies. Despite all efforts, therapy remains limited, and ARDS is… Read more »
Positive Patch-Test Reactions to Essential Oils in Consecutive Patients: Results From North America and Central Europe
Warshaw EM, Zug KA, Belsito DV, Fowler JF Jr, DeKoven JG, Sasseville D, Maibach HI, Mathias CGT, DeLeo VA, Taylor JS, Fransway AF, Marks JG Jr, Pratt MD, Zirwas MJ, Geier J, Uter W Dermatitis, 2017 ABSTRACT: BACKGROUND: Synthetic fragrances and natural essential oils (EOs) are used in perfumery and found in various cosmetics. Essential oils are also increasingly used to promote wellness. In previous studies, the sensitization potential of some EOs has been identified; however,… Read more »
Prebiotic Potential and Chemical Composition of Seven Culinary Spice Extracts
Lu QY, Summanen PH, Lee RP, Huang J, Henning SM, Heber D, Finegold SM, Li Z Journal of Food Science, 2017 ABSTRACT: The objective of this study was to investigate prebiotic potential, chemical composition, and antioxidant capacity of spice extracts. Seven culinary spices including black pepper, cayenne pepper, cinnamon, ginger, Mediterranean oregano, rosemary, and turmeric were extracted with boiling water. Major chemical… Read more »
Metabolic Products of Linalool and Modulation of GABAA Receptors
Milanos S, Elsharif SA, Janzen D, Buettner A, Villmann C Frontiers in Chemistry, 2017 ABSTRACT: Terpenoids are major subcomponents in aroma substances which harbor sedative physiological potential. We have demonstrated that various monoterpenoids such as the acyclic linalool enhance GABAergic currents in an allosteric manner in vitro upon overexpression of inhibitory α1β2 GABAA receptors in various expression systems. However, in plants or humans, i.e.,… Read more »
Neuroprotective Effects of β-Caryophyllene against Dopaminergic Neuron Injury in a Murine Model of Parkinson’s Disease Induced by MPTP
Viveros-Paredes JM, González-Castañeda RE, Gertsch J, Chaparro-Huerta V, López-Roa RI, Vázquez-Valls E, Beas-Zarate C, Camins-Espuny A, Flores-Soto ME Pharmaceuticals (Basel, Switzerland), 2017 ABSTRACT: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders and is characterized by the loss of dopaminergic neurons in the substantia nigra (SN). Although the causes of PD are not understood, evidence suggests that its pathogenesis is associated… Read more »