β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway

Cheng Y, Dong Z, Liu S Pharmacology, 2014 ABSTRACT: BACKGROUND/AIMS: The activation of cannabinoid receptor 2 (CB2) has the beneficial effect of reducing neuroinflammatory response in the treatment of Alzheimer’s disease (AD) and is suggested to trigger the peroxisome proliferator-activated receptor-γ (PPARγ) pathway; agonists of both receptors improve AD. Recently, the plant metabolite β-caryophyllene was… Read more »

The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines

Ambrož M, Matoušková P, Skarka A, Zajdlová M, Žáková K, Skálová L Molecules, 2017 ABSTRACT: β-caryophyllene oxide (CAO), α-humulene (HUM), trans-nerolidol (NER) and valencene (VAL) are constituents of the essential oil of Myrica rubra (MEO), which has significant antiproliferative effect in various cancer cell lines. In the present study, we compared the antiproliferative effect of… Read more »

Global transcriptional response of Escherichia coli MG1655 cells exposed to the oxygenated monoterpenes citral and carvacrol

Chueca B, Pérez-Sáez E, Pagán R, García-Gonzalo D International Journal of Food Microbiology, 2017 ABSTRACT: DNA microarrays were used to study the mechanism of bacterial inactivation by carvacrol and citral. After 10-min treatments of Escherichia coli MG1655 cells with 100 and 50ppm of carvacrol and citral, 76 and 156 genes demonstrated significant transcriptional differences (p≤0.05),… Read more »

Effect of essential oil mouthwashes on plaque and gingivitis

Richards D Journal of Evidence-Based Dental Practice, 2017 ABSTRACT: Data sources: Medline, Embase, LILACS and Scopus database. Study selection: Studies were screened independently by three reviewers. Randomised controlled trials with a minimum of six months follow-up of daily use of essential oils-containing (EO) mouthwashes compared with placebo, flossing or cetylpyridinium chloride (CPC) as adjuncts to… Read more »

The repellent efficacy of eleven essential oils against adult Dermacentor reticulatus ticks

Štefanidesová K, Škultéty Ľ, Sparagano OAE, Špitalská E Ticks and Tick-borne Diseases, 2017 ABSTRACT: Dermacentor reticulatus ticks are among the most important arthropod vectors of zoonotic disease agents in Europe. Eleven essential oils, namely basil (Ocimum basilicum), bergamot (Citrus bergamia), clove bud (Syzygium aromaticum), citronella (Cymbopogon winterianus), creeping thyme (Thymus serpyllum), lavender (Lavandula angustifolia), lemon-scented… Read more »

A systematic review of the effect of inhaled essential oils on sleep

Lillehei AS, Halcon LL Journal of Alternative and Complementary Medicine, 2014 ABSTRACT: OBJECTIVE: Sleep disturbances are recognized as an important health and public health problem that affects physical, mental, and emotional health and well-being. Inhalation of essential oils may be a safe alternative to pharmaceutical interventions for mild to moderate sleep disturbances. Quantitative human studies… Read more »

Sedative effects of vapor inhalation of agarwood oil and spikenard extract and identification of their active components

Takemoto H, Ito M, Shiraki T, Yagura T, Honda G Journal of Natural Medicines, 2007 ABSTRACT: Agarwood oil and spikenard extract were examined for their sedative activity using a spontaneous vapor administration system. It was shown that inhalation of agarwood oil vapor sedated mice. The main volatile constituents of the oil were found to be… Read more »

Aroma oil therapy in palliative care: a pilot study with physiological parameters in conscious as well as unconscious patients

Goepfert M, Liebl P, Herth N, Ciarlo G, Buentzel J, Huebner J Journal of Cancer Research and Clinical Oncology, 2017 ABSTRACT: OBJECTIVE: The aim of this pilot study is to analyze the reactions of healthy test persons and conscious as well as unconscious palliative patients to aroma stimuli. PATIENTS AND METHODS: In a randomized controlled study,… Read more »