Mosbah H, Chahdoura H, Kammoun J, Hlila MB, Louati H, Hammami S, Flamini G, Achour L, Selmi B BMC Complementary and Alternative Medicine, 2018 ABSTRACT: BACKGROUND: α-glucosidase is a therapeutic target for diabetes mellitus (DM) and α-glucosidase inhibitors play a vital role in the treatments for the disease. Furthermore, xanthine oxidase (XO) is a key… Read more »
Cymbopogon citratus and Cymbopogon giganteus essential oils have cytotoxic effects on tumor cell cultures. Identification of citral as a new putative anti-proliferative molecule
Bayala B, Bassole IHN, Maqdasy S, Baron S, Simpore J, Lobaccaro JA Biochimie, 2018 ABSTRACT: Cymbopogon species are used as traditional remedies in Burkina Faso for treating several diseases. We aimed to study the effects of their essential oils on cancer cell lines. For that purpose, Cymbopogon citratus (DC.) Stapf. and Cymbopogon giganteus Chiov. were… Read more »
Targeting oxidative stress, acetylcholinesterase, proinflammatory cytokine, dopamine and GABA by eucalyptus oil (Eucalyptus globulus) to alleviate ketamine-induced psychosis in rats
Yadav M, Jindal DK, Parle M, Kumar A, Dhingra S Inflammopharmacology, 2018 ABSTRACT: Essential oil of eucalyptus species is among the most common traded essential oils in the world. There is an increasing interest in the application of eucalyptus oil as a natural additive in food and pharmaceutical industry. The present study was undertaken to… Read more »
Cinnamomum zeylanicum bark essential oil induces cell wall remodelling and spindle defects in Candida albicans
Shahina Z, El-Ganiny AM, Minion J, Whiteway M, Sultana T, Dahms TES Fungal Biology and Biotechnology, 2018 ABSTRACT: BACKGROUND: Cinnamon (Cinnamomum zeylanicum) bark extract exhibits potent inhibitory activity against Candida albicans but the antifungal mechanisms of this essential oil remain largely unexplored. RESULTS: We analyzed the impact of cinnamon bark oil on C. albicans RSY150,… Read more »
Chemical composition analysis and in vitro biological activities of ten essential oils in human skin cells
Han X, Beaumont C, Stevens N Biochimie Open, 2017 ABSTRACT: Research on the biological effects of essential oils on human skin cells is scarce. In the current study, we primarily explored the biological activities of 10 essential oils (nine single and one blend) in a pre-inflamed human dermal fibroblast system that simulated chronic inflammation. We… Read more »
Lemongrass (Cymbopogon flexuosus) essential oil demonstrated anti-inflammatory effect in pre-inflamed human dermal fibroblasts
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: Lemongrass (Cymbopogon flexuosus) essential oil (LEO), which has citral as its main component, has exhibited anti-inflammatory effect in both animal and human cells. In this study, we evaluated the anti-inflammatory activity of a commercially available LEO in pre-inflamed human dermal fibroblasts. We first studied the impact of… Read more »
Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano (Origanum vulgare) essential oil in a human skin disease model
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: The use of oregano (Origanum vulgare) essential oil (OEO) has become popular in skin care products. However, scientific research regarding its effects on human skin cells is scarce. In this study, we investigated the biological activity of a commercially available OEO, which is high in carvacrol content,… Read more »
Arborvitae (Thuja plicata) essential oil significantly inhibited critical inflammation- and tissue remodeling-related proteins and genes in human dermal fibroblasts
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: Arborvitae (Thuja plicata) essential oil (AEO) is becoming increasingly popular in skincare, although its biological activity in human skin cells has not been investigated. Therefore, we sought to study AEO’s effect on 17 important protein biomarkers that are closely related to inflammation and tissue remodeling by using… Read more »
Biological activities of frankincense essential oil in human dermal fibroblasts
Han X, Rodriguez D, Parker TL Biochimie Open, 2017 ABSTRACT: Although frankincense essential oil (FREO) has become increasingly popular in skin care, research on its biological activities in human skin cells is scarce, if not completely absent. In the current study, we explored the biological activities of FREO in pre-inflamed human dermal fibroblasts by analyzing… Read more »
Selected terpenes from leaves of Ocimum basilicum L. induce hemoglobin accumulation in human K562 cells
Giordana F, Nicola M, Valentina C, Torricelli P, Beninati S, Tagliati F, Mischiati C Fitoterapia, 2018 ABSTRACT: Re-expression of fetal hemoglobin (HbF) was proposed as a possible therapeutic strategy for β-haemoglobinopathies. Although several inducers of HbF were tested in clinical trials, only hydroxyurea (HU) received FDA approval. Despite it produced adequate HbF levels only in… Read more »