Shanmuganathan B, Suryanarayanan V, Sathya S, Narenkumar M, Singh SK, Ruckmani K, Pandima Devi K European Journal of Medicinal Chemistry, 2017 ABSTRACT: Alzheimer’s disease (AD) is a life-threatening neurodegenerative disorder leading to dementia, with a progressive decline in memory and other thinking skills of elderly populace. Of the multiple etiological factors of AD, the accumulation… Read more »
In vitro Protoscolicidal Effects of Cinnamomum zeylanicum Essential Oil and Its Toxicity in Mice
Mahmoudvand H, Mahmoudvand H, Oliaee RT, Kareshk AT, Mirbadie SR, Aflatoonian MR Pharmacognosy Magazine, 2017 BACKGROUND: This study investigates the scolicidal effects of Cinnamomum zeylanicum essential oilagainst the protoscoleces of hydatid cysts and its toxicity in the mice model. MATERIALS AND METHODS: Gas chromatography/mass spectroscopy analyses were used to identify the constituents of essential oil. Protoscoleces were treated… Read more »
Apoptotic Effect of Nigella sativa on Human Lymphoma U937 Cells
Arslan BA, Isik FB, Gur H, Ozen F, Catal T Pharmacognosy Magazine, 2017 OBJECTIVE: Nigella sativa is from botanical Ranunculaceae family and commonly known as black seed. Apoptotic effect of N. sativa and its apoptotic signaling pathways on U937 lymphoma cells are unknown. MATERIALS AND METHODS: In this study, we investigated selective cytotoxic and apoptotic effects of N. sativa extract… Read more »
Construction of cell factories for high production of nerolidol in Saccharomyces cerevisiae (Chinese)
Zhang LL, Ma XL, Wang D, Yu P, Huang LQ, Zhang XL, Dai ZB Zhongguo Zhong Yao Za Zhi, 2017 ABSTRACT: Nerolidol is an important constituent of terpenoid essential oil and has excellent anti-tumor, anti-bacterial, and anti-oxidative properties. For realizing heterogenous production of nerolidol, our research firstly integrated the codon-optimized Actinidia sinensis nerolidol synthase gene (NES) into the… Read more »
Proteinaceous microspheres as a delivery system for carvacrol and thymol in antibacterial applications
Sokolik CG, Ben-Shabat-Binyamini R, Gedanken A, Lellouche JP Ultrasonics & Sonochemistry, 2017 ABSTRACT: There is an urgent need for new materials with antimicrobial activity. Phenolic essential oil (EO) compounds with Generally Recognized As Safe (GRAS) status are attractive candidates, but they need suitable delivery systems to overcome specific drawbacks. Core-shell microspheres (MSs) of Bovine Serum Albumin (BSA)… Read more »
Medicinally important aromatic plants with radioprotective activity.
Samarth RM, Samarth M, Matsumoto Y Future Science OA, 2017 ABSTRACT: Aromatic plants are often used as natural medicines because of their remedial and inherent pharmacological properties. Looking into natural resources, particularly products of plant origin, has become an exciting area of research in drug discovery and development. Aromatic plants are mainly exploited for essential oil extraction… Read more »
Lactoferrin, chitosan and Melaleuca alternifolia-natural products that show promise in candidiasis treatment
Felipe LO, Júnior WFDS, Araújo KC, Fabrino DL Brazilian Journal of Microbiology, 2017 ABSTRACT: The evolution of microorganisms resistant to many medicines has become a major challenge for the scientific community around the world. Motivated by the gravity of such a situation, the World Health Organization released a report in 2014 with the aim of… Read more »
Behavior of detoxifying enzymes of Aedes aegypti exposed to girgensohnine alkaloid analog and Cymbopogon flexuosus essential oil
Carreño Otero AL, Palacio-Cortés AM, Navarro-Silva MA, Kouznetsov VV, Duque L JE Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2017 ABSTRACT: Because mosquito control depend on the use of commercial insecticides and resistance has been described in some of them, there is a need to explore new molecules no resistant. In vivo effects… Read more »
In Vitro Evaluation of Essential Oils Derived from Piper nigrum (Piperaceae) and Citrus limonum (Rutaceae) against the Tick Rhipicephalus (Boophilus) microplus (Acari: Ixodidae)
Vinturelle R, Mattos C, Meloni J, Nogueira J, Nunes MJ, Vaz IS Jr, Rocha L, Lione V, Castro HC, Chagas EFD Biochemistry Research International, 2017 ABSTRACT: The present research aimed to study the chemical composition and acaricidal activity of Citrus limonum and Piper nigrum essential oils against the cattle tick Rhipicephalus microplus. GC-MS analysis of C. limonumessential oil showed limonene (50.3%), β-pinene (14.4%), and γ-terpinene… Read more »
Chemical composition and evaluation of antinociceptive activity of the essential oil of Stevia serrata Cav. from Guatemala
Reis Simas DL, Mérida-Reyes MS, Muñoz-Wug MA, Cordeiro MS, Giorno TBS, Taracena EA, Oliva-Hernández BE, Martínez-Arévalo JV, Fernandes PD, Pérez-Sabino JF, Jorge Ribeiro da Silva A Natural Product Research, 2017 ABSTRACT: The composition and the antinociceptive activity of the essential oil of Stevia serrata Cav. from a population located in the west highlands of Guatemala were evaluated…. Read more »