Neuron differentiation-related genes are up-regulated in the hypothalamus of odorant-inhaling rats subjected to acute restraint stress.

Nakamura A, Fujiwara S, Ishijima T, Okada S, Nakai Y, Matsumoto I, Misaka T, Abe K Journal of agricultural and food chemistry, 2010 ABSTRACT: To elucidate some physiopsychological effects of a pleasant odor, we analyzed gene expression profiles in the hypothalamus of rats which, under a restraint-stressed condition, inhaled (R)-(-)-linalool. Consequently, 697 probe sets showed… Read more »

Linalyl acetate as a major ingredient of lavender essential oil relaxes the rabbit vascular smooth muscle through dephosphorylation of myosin light chain

Koto R, Imamura M, Watanabe C, Obayashi S, Shiraishi M, Sasaki Y, Azuma H Journal of cardiovascular pharmacology, 2006 ABSTRACT: In a preliminary experiment, we found that lavender essential oil relaxes vascular smooth muscle. Thus, the present experiments were designed to investigate the relaxation mechanism of linalyl acetate as the major ingredient of lavender essential… Read more »

Stress repression in restrained rats by (R)-(-)-linalool inhalation and gene expression profiling of their whole blood cells

Nakamura A, Fujiwara S, Matsumoto I, Abe K Journal of agricultural and food chemistry, 2009 ABSTRACT: As an attempt to quantitatively analyze the physiopsychological effects elicited by odorants, white blood cells and gene expression were profiled in the whole blood of the rats exposed to (R)-(-)-linalool during restraint stress for 2 h. In neutrophils and… Read more »

Inhaled linalool-induced sedation in mice

Linck VM, da Silva AL, Figueiró M, Piato AL, Herrmann AP, Dupont Birck F, Caramão EB, Nunes DS, Moreno PR, Elisabetsky E Phytomedicine : international journal of phytotherapy and phytopharmacology ABSTRACT: Linalool is a monoterpene often found as a major component of essential oils obtained from aromatic plant species, many of which are used in… Read more »

Phytoremediation of Cu and Zn by vetiver grass in mine soils amended with humic acids

Vargas C, Pérez-Esteban J, Escolástico C, Masaguer A, Moliner Environmental science and pollution research international, 2016 ABSTRACT: Phytoremediation of contaminated mine soils requires the use of fast-growing, deep-rooted, high-biomass, and metal-tolerant plants with the application of soil amendments that promote metal uptake by plants. A pot experiment was performed to evaluate the combined use of… Read more »

Diterpenes: Advances in Neurobiological Drug Research

Islam MT, da Silva CB, de Alencar MV, Paz MF, Almeida FR, Melo-Cavalcante AA Phytotherapy research, 2016 ABSTRACT: A significant number of studies have been performed with diterpene effect on the brain. Our study aims to make a systematic revision on them. The initial purpose of this review was to screen diterpenes with neurological activity,… Read more »

Patch Testing with Main Sensitizers Does Not Detect All Cases of Contact Allergy to Oxidized Lavender Oil

Hagvall L, Christensson JB Acta dermato-venereologica, 2016 ABSTRACT: Lavender oil is an essential oil obtained from lavender (Lavendula angustifolia). The main components linalool and linalyl acetate have been shown to autoxidize in contact with oxygen in the air, forming sensitizing hydroperoxides. Patients with suspected allergic contact dermatitis were consecutively patch-tested with oxidized lavender oil 6%… Read more »

The effects of Melissa officinalis (lemon balm) pretreatment on the resistance of the heart to myocardial injury

Joukar S, Asadipour H, Sheibani M, Najafipour H, Dabiri S Pharmaceutical biology, 2016 ABSTRACT: CONTEXT: The antihyperlipidemic, antiarrhythmic, neuroprotective and hepatoprotective effects of Melissa officinalis L. (Lamiaceae) have been reported. However, no study has examined its effects on the resistance of the heart to stressful conditions. OBJECTIVE: The objective of this study is to evaluate… Read more »

Inhibitory effects of rosemary (Rosemarinus officinalis L.) essential oil on pathogenicity of irradiated and non-irradiated Pseudomonas aeruginosa

Araby E, El-Tablawy SY Journal of photochemistry and photobiology. B, Biology. 2016 ABSTRACT: Pseudomonas aeruginosa is considered one of the most important opportunistic pathogens, which is responsible for nosocomial infections. The complex pathophysiology of infections associated with P. aeruginosa is due to its ability to grow in a biofilm mass and to produce a large… Read more »

Unraveling the rat blood genome-wide transcriptome after oral administration of lavender oil by a two-color dye-swap DNA microarray approach

Hori M, Kubo H, Shibato J, Saito T, Ogawa T, Wakamori M, Masuo Y, Shioda S, Rakwal R Genomics data, 2016 ABSTRACT: Lavender oil (LO) is a commonly used essential oil in aromatherapy as non-traditional medicine. With an aim to demonstrate LO effects on the body, we have recently established an animal model investigating the… Read more »