Chemistry and Pharmacology of Citrus sinensis

Favela-Hernández JM, González-Santiago O, Ramírez-Cabrera MA, Esquivel-Ferriño PC, Camacho-Corona Mdel R Molecules, 2016 ABSTRACT: Presently the search for new drugs from natural resources is of growing interest to the pharmaceutical industry. Natural products have been the source of new drugs since ancient times. Plants are a good source of secondary metabolites which have been found… Read more »

Zingiberene attenuates hydrogen peroxide-induced toxicity in neuronal cells

Togar B, Türkez H, Stefano AD, Tatar A, Cetin D Human & experimental toxicology, 2015 ABSTRACT: In this experimental design, we explored the neuroprotective potential of zingiberene (ZGB), a monocyclic sesquiterpene, in hydrogen peroxide (H2O2)-induced toxicity in newborn rat cerebral cortex cell cultures for the first time. The rats were exposed to H2O2 for 6… Read more »

Essential oils in the management of the donkey louse, Bovicola ocellatus

Ellse L, Sands B, Burden FA, Wall R Equine veterinary journal, 2016 ABSTRACT: REASONS FOR PERFORMING STUDY: Chewing lice are widespread and clinically compromising parasites of livestock and equids. Their management is complicated by growing levels of resistance to commonly applied insecticides. Hence, the development of novel approaches to their control is of major clinical… Read more »

The anti-dermatophyte activity of Commiphora molmol

Mahboubi M, Mohammad Taghizadeh Kashani L Pharmaceutical biology, 2016 ABSTRACT: CONTEXT: Commiphora molmol Engl (Burseraceae) or myrrh has been traditionally used for the treatment of skin fungal infections. OBJECTIVE: This study evaluates the antifungal activity of myrrh ethanol extract and essential oil against skin dermatophytes. MATERIALS AND METHODS: The antifungal evaluations were performed by the… Read more »

Ocimum basilicum: Antibacterial activity and association study with antibiotics against bacteria of clinical importance

Araújo SV, Pereira SJ, de Luna FPH, Fernanda RFA, Douglas MCH, Beuttenmuller NAL, Oliveira LE Pharmaceutical biology, 2016 ABSTRACT: Ocimum basilicum: Antibacterial activity and association study with antibiotics against bacteria of clinical importance. – PubMed – NCBI CONTEXT: Ocimum basilicum L. (Lamiaceae), popularly known as basil, is part of a group of medicinal plants widely… Read more »

Cytotoxicity and genotoxicity of zingiberene on different neuron cell lines in vitro

Togar B, Turkez H, Tatar A, Hacimuftuoglu A, Geyikoglu F Cytotechnology, 2015 ABSTRACT: The main objective of this study is to investigate the cytotoxic, genotoxic and antioxidant properties of zingiberene (ZBN) in an in vitro rat brain cell culture study. The cytotoxic effect was determined against the rat neuron and N2a neuroblastoma (N2a-NB) cell lines… Read more »

Furanodiene enhances the anti-cancer effects of doxorubicin on ERα-negative breast cancer cells in vitro

Zhong ZF, Qiang WA, Wang CM, Tan W, Wang YT European journal of pharmacology, 2016 ABSTRACT: Furanodiene is a natural product isolated from Rhizoma curcumae, and exhibits broad-spectrum anti-cancer activities in vitro and in vivo. Our previous study proved that furanodiene could increase growth inhibition of steroidal agent in ERα-positive breast cancer cells, but whether… Read more »

Larvicidal potential of carvacrol and terpinen-4-ol from the essential oil of Origanum vulgare (Lamiaceae) against Anopheles stephensi, Anopheles subpictus, Culex quinquefasciatus and Culex tritaeniorhynchus (Diptera: Culicidae)

Govindarajan M, Rajeswary M, Hoti SL, Benelli G Research in veterinary science, 2016 ABSTRACT: Mosquito-borne diseases represent a deadly threat for millions of people worldwide. However, the use of synthetic insecticides to control Culicidae may lead to resistance, high operational costs and adverse non-target effects. Nowadays, plant-borne mosquitocides may serve as suitable alternative in the… Read more »

Antioxidant properties of coriander essential oil and linalool and their potential to control Campylobacter spp

Duarte A, Luís A, Oleastro M, Domingues FC Food Control, 2016 ABSTRACT: Foodborne diseases remain common around the world with Campylobacteriosis being the most commonly reported zoonosis in the European Union in 2013. Campylobacter jejuni and Campylobacter coli are the main species associated with human illness. Furthermore, Campylobacter can develop biofilms which is becoming a major… Read more »

Effects of TRP channel agonist ingestion on metabolism and autonomic nervous system in a randomized clinical trial of healthy subjects

Michlig S, Merlini JM, Beaumont M, Ledda M, Tavenard A, Mukherjee R, Camacho S, le Coutre J Scientific reports, 2016 ABSTRACT: Various lines of published evidence have already demonstrated the impact of TRPV1 agonists on energetic metabolism through the stimulation of the sympathetic nervous system (SNS). This study presents a trial investigating if stimulation of… Read more »