β-Bisabolene, a Sesquiterpene from the Essential Oil Extract of Opoponax (Commiphora guidottii), Exhibits Cytotoxicity in Breast Cancer Cell Lines

Yeo SK, Ali AY, Hayward OA, Turnham D, Jackson T, Bowen ID, Clarkson R Phytotherapy research : PTR, 2016 ABSTRACT: The essential oils from Commiphora species have for centuries been recognized to possess medicinal properties. Here, we performed gas chromatography-mass spectrometry on the essential oil from opoponax (Commiphora guidotti) and identified bisabolene isomers as the… Read more »

Biphasic cardiovascular and respiratory effects induced by β-citronellol

Ribeiro-Filho HV, de Souza Silva CM, de Siqueira RJ, Lahlou S, Dos Santos AA, Magalhães PJ European journal of pharmacology, 2016 ABSTRACT: β-Citronellol is a monoterpene found in the essential oil of various plants with antihypertensive properties. In fact, β-citronellol possesses hypotensive actions due to its vasodilator abilities. Here we aimed to show that β-citronellol… Read more »

Modification of sleep-waking and electroencephalogram induced by vetiver essential oil inhalation

Cheaha D, Issuriya A, Manor R, Kwangjai J, Rujiralai T, Kumarnsit E Journal of Intercultural Ethnopharmacology, 2016 ABSTRACT: Background: Essential oils (EOs) have been claimed to modulate mental functions though the most of data were obtained from subjective methods of assessment. Direct effects of EO on brain function remained largely to be confirmed with scientific… Read more »

Anethole restores delayed gastric emptying and impaired gastric accommodation in rodents

Asano T, Aida S, Suemasu S, Mizushima T Biochemical and biophysical research communications, 2016 ABSTRACT: Functional dyspepsia (FD), a functional gastrointestinal disorder, is characterized by persistent or recurrent postprandial upper abdominal discomfort and epigastric pain. The high prevalence of FD and associated healthcare costs suggests that treatment of this condition by methods other than prescribed… Read more »

Antioxidant activity of linalool in patients with carpal tunnel syndrome

Seol GH, Kang P, Lee HS, Seol GH BMC neurology, 2016 ABSTRACT: BACKGROUND: Carpal tunnel syndrome (CTS) is a common peripheral neuropathy and ischemic-reperfusion injury. Oxidative stress is considered a major cause of CTS. Linalool, a component of essential oils, has antioxidant activity. This study was designed to determine the effects of linalool inhalation on… Read more »

Change in Chemical Composition of Sweet Basil (Ocimum basilicum L.) Essential Oil Caused by Alfalfa mosaic virus

Bruni R, Bellardi MG, Parrella G J Phytopathol, 2015 ABSTRACT: The effects of Alfalfa mosaic virus (AMV) infection on essential oil (EO) content and composition of a Sweet Basil cv. Gigante di Napoli were evaluated. A 10-fold lower extraction yield from infected plants was observed, suggesting that morphological alterations induced by the disease may affect… Read more »

Combined non-adaptive light and smell stimuli lowered blood pressure, reduced heart rate and reduced negative affect

Dong S, Jacob TJ Physiology & behavior, 2016 ABSTRACT: Bright light therapy has been shown to have a positive impact on seasonal affective disorder (SAD), depression and anxiety. Smell has also has been shown to have effects on mood, stress, anxiety and depression. The objective of this study was to investigate the effect of the… Read more »

Eugenol, α-pinene and β-caryophyllene from Plectranthus barbatus essential oil as eco-friendly larvicides against malaria, dengue and Japanese encephalitis mosquito vectors

Govindarajan M, Rajeswary M, Hoti SL, Bhattacharyya A, Benelli G Parasitology research, 2016 ABSTRACT: Mosquito-borne diseases represent a deadly threat for millions of people worldwide. Eco-friendly mosquitocides are a priority. In Ayurvedic medicine, Plectranthus species have been used to treat heart disease, convulsions, spasmodic pain and painful urination. In this research, we evaluated the acute… Read more »

Relationship Between Emotional Behavior in Mice and the Concentration of (+)-α-Santalol in the Brain

Satou T, Ogawa Y, Koike Kazuo Phytother Res, 2015 ABSTRACT: We previously reported finding anxiolytic-like activity for sandalwood oil after administration in mice. In this report, we further investigated the emotional behavior associated with inhaled or intraperitoneally administered (+)-α-santalol, the main component of sandalwood oil, in addition to examining whether pharmacological or neurological transfers are… Read more »

α- and β-Santalols Directly Interact with Tubulin and Cause Mitotic Arrest and Cytotoxicity in Oral Cancer Cells

Lee B, Bohmann J, Reeves T, Levenson C, Risinger AL Journal of natural products, 2015 ABSTRACT: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, with no major advancements in treatment over the past 40 years. The current study explores the biological effects of East Indian sandalwood oil (EISO) and… Read more »