Aneesa NN, Anitha R, Varghese S Journal of Pharmacy and Bioallied Sciences, 2019 ABSTRACT: CONTEXT: Ajwain oil is an essential oil with thymol as its major constituent which is known for many pharmacological activities. AIMS: To evaluate the anti-hyperglycaemic potential of ajwain oil using different in vitro models. METHODS AND MATERIAL: In vitro α-amylase and… Read more »
Thymol
- Backbone: Monoterpene
- Functional Group: Phenol
Genoprotective Effects of Essential Oil Compounds Against Oxidative and Methylated DNA Damage in Human Colon Cancer Cells
Thapa D, Richardson AJ, Zweifel B, Wallace RJ, Gratz SW Journal of Food Science, 2019 ABSTRACT: Essential oils (EO) are widely used in foods as flavoring and preservative agents. Many of the biological activities of EO have been attributed to major essential oil compounds (EOC) but their direct interaction with colonic epithelial cells and their… Read more »
Antibacterial activity of traditional spices against lower respiratory tract pathogens: combinatorial effects of Trachyspermum ammi essential oil with conventional antibiotics
Grădinaru AC, Trifan A, Şpac A, Brebu M, Miron A, Aprotosoaie AC Letters in Applied Microbiology, 2018 ABSTRACT: The aim of this study was to investigate the effects of ajowan essential oil (AjEO)/thymol and antibiotics combinations against three standard strains and six resistant clinical isolates of major respiratory bacteria (Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus… Read more »
Essential Oil as a Potential Anti-Acne Topical Nanoemulsion-In Vitro and In Vivo Study
Taleb MH, Abdeltawab NF, Shamma RN, Abdelgayed SS, Mohamed SS, Farag MA, Ramadan MA Molecules, 2018 ABSTRACT: Antibiotics are often prescribed in acne treatment; however, Propionibacterium acnes and Staphylococcus epidermidis, the two of the major acne-associated bacteria, developed antibiotic resistance. Essential oils (EOs) present a natural, safe, efficacious and multifunctional alternative treatment. This study aimed… Read more »
The anticonvulsant and anti-plasmid conjugation potential of Thymus vulgaris chemistry: An in vivo murine and in vitro study
Skalicka-Woźniak K, Walasek M, Aljarba TM, Stapleton P, Gibbons S, Xiao J, Łuszczki JJ Food and Chemical Toxicology, 2018 ABSTRACT: The high-performance counter-current chromatography was used for the efficient purification of single constituents from Thymus vulgaris essential oil. Mixtures of n-heptane, ethyl acetate, methanol, and water (5:2:5:2 and 4:1:4:1 v/v), allowed purification of eugenol, 1-octen-3-… Read more »
Oregano Essential Oil Attenuates RAW264.7 Cells from Lipopolysaccharide-Induced Inflammatory Response through Regulating NADPH Oxidase Activation-Driven Oxidative Stress
Cheng C, Zou Y, Peng J Molecules, 2018 ABSTRACT: Oregano is an aromatic plant widely distributed throughout the Mediterranean area and in Asia. Recent studies have revealed that the anti-inflammatory effect of essential oil in this plant. However, the mechanisms underlying the therapeutic potential have not been well elucidated. This study determined whether oregano essential… Read more »
Effects of Essential Oil of Satureja bachtiarica Bunge in a Rat Model of Reserpine-Induced Depression
Bakhtiarpoor M, Setorki M, Kaffashian MR Iran Journal of Medical Sciences, 2018 ABSTRACT: BACKGROUND: Due to the unfavorable side effects of some commonly used chemical drugs, the trend in the public has shifted towards using herbal medicines to treat central nervous system disorders like depression. The present experimental study was designed to evaluate the effect… Read more »
Transcriptomic approach and membrane fatty acid analysis to study the response mechanisms of Escherichia coli to thyme essential oil, carvacrol, 2-(E)-hexanal and citral exposure
Siroli L, Braschi G, De jong A, Kok J, Patrignani F, Lanciotti R Journal of Applied Microbiology, 2018 ABSTRACT: AIMS: The application of essential oils (EOs) and their components as food preservatives is promising but requires a deeper understanding of their mechanisms of action. This study aims to evaluate the effects of thyme EO, carvacrol,… Read more »
Thymus essential oil extraction, characterization and incorporation in phospholipid vesicles for the antioxidant/antibacterial treatment of oral cavity diseases
Manconi M, Petretto G, D’hallewin G, Escribano E, Milia E, Pinna R, Palmieri A, Firoznezhad M, Peris JE, Usach I, Fadda AM, Caddeo C, Manca ML Colloids and Surfaces B: Biointerfaces, 2018 ABSTRACT: The aim of the work was to extract, characterize, and formulate Thymus capitatus (Tymbra capitata) essential oil in phospholipid vesicles: liposomes, glycerosomes… Read more »
Antidepressant-Like Effect of Lippia sidoides (Verbenaceae) Essential Oil and Its Major Compound Thymol in Mice
Parente MSR, Custódio FR, Cardoso NA, Lima MJA, Melo TS, Linhares MI, Siqueira RMP, Nascimento AÁD, Catunda Júnior FEA, Melo CTV Scientia Pharmaceutica, 2018 ABSTRACT: Depression is a common disease affecting more than 300 million people worldwide. Since Lippia sidoides has shown central nervous system effects in previous works, we aimed to investigate the effect… Read more »