Thymoquinone

  • Backbone: Monoterpene
  • Functional Group: Other

Deodorizing Substance in Black Cumin (Nigella sativa L.) Seed Oil

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Nakasugi T, Murakawa T, Shibuya K, Morimoto M Journal of Oleo Science, 2017 ABSTRACT: A deodorizing substance in black cumin (Nigella sativa L.), a spice for curry and vegetable foods in Southwest Asia, was examined. The essential oil prepared from the seeds of this plant exhibited strong deodorizing activity against methyl mercaptan, which is a main factor in oral malodor…. Read more »

Development of antimicrobial nanoemulsion-based delivery systems against selected pathogenic bacteria using a thymol rich Thymus daenensis essential oil

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Ghaderi L, Moghimi R, Aliahmadi A, McClements DJ, Rafati H Journal of Applied Microbiology, 2017 ABSTRACT: AIMS: Thymol rich medicinal plants have been used in traditional medicine to relieve infectious diseases. However, the application of essential oils as medicine is limited by its low water-solubility and high vapor pressure. The objective of this study was to produce stable nanoemulsions of Thymus daenensis oil in… Read more »

Potential role of natural compounds as anti-angiogenic agents in cancer

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Shanmugam MK, Warrier S, Kumar AP, Sethi G, Arfuso F Current Vascular Pharmacology, 2017 ABSTRACT: BACKGROUND: Neovascularization, also known as angiogenesis, is the process of capillary sprouting from pre-existing blood vessels. This physiological process is a hallmark event in normal embryonic development as blood vessels generally supply both oxygen and nutrients to the cells of the body. Any disruption… Read more »

The Effect of Thymoquinone on Apoptosis of SK-OV-3 Ovarian Cancer Cell by Regulation of Bcl-2 and Bax

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Liu X, Dong J, Cai W, Pan Y, Li R, Li B International Journal of Gynecological Cancer, 2017 ABSTRACT: OBJECTIVE: We aim to determine how cisplatin, thymoquinone (TQ), and combination regimen can affect apoptosis of cultured SK-OV-3 cells. We also want to explore the mechanism of these influences on the cells’ apoptosis by Bcl-2 and Bax gene. METHOD/MATERIALS: Cell Counting Kit-8 assay… Read more »