Terpenes, Phenylpropanoids, Sulfur and Other Essential Oil Constituents as Inhibitors of Cholinesterases

Politeo O, Burcul F, Blazevic I, Radan M Current Medicinal Chemistry, 2018 ABSTRACT: Essential oils constituents are a diverse family of low molecular weight organic compounds with comprehensive biological activity. According to their chemical structure these active compounds can be divided into four major groups: terpenes, terpenoids, phenylpropenes, and “others”. In addition, they may contain… Read more »

Antimicrobial Essential Oil Combinations to Combat Foot Odour

Orchard A, Viljoen A, van Vuuren SF Planta Medica, 2018 ABSTRACT: Foot odour (bromodosis) is an embarrassing and perplexing condition mostly caused by bacteria of the Brevibacterium species. Essential oils are a credible option as an affordable treatment of odour and contribute towards antimicrobial efficacy. Therefore, this study sets out to investigate the antimicrobial activity… Read more »

Structure-activity modelling of essential oils, their components, and key molecular parameters and descriptors

Owen L, Laird K, Wilson PB Molecular and Cellular Probes, 2017 ABSTRACT: Many essential oil components are known to possess broad spectrum antimicrobial activity, including against antibiotic resistant bacteria. These compounds may be a useful source of new and novel antimicrobials. However, there is limited research on the structure-activity relationship (SAR) of essential oil compounds,… Read more »

Effects of patchouli and cinnamon essential oils on biofilm and hyphae formation by Candida species

Farisa Banu S, Rubini D, Shanmugavelan P, Murugan R, Gowrishankar S, Karutha Pandian S, Nithyanand P Journal de Mycologie Medicale, 2018 ABSTRACT: The prevalence and fatality rates with biofilm-associated candidal infections have remained a challenge to the medical fraternity despite major advances in the field of antifungal therapy. Traditionally, essential oils (EOs) from the aromatic… Read more »

Solid Lipid Nanoparticles (SLN) carrying Eugenia caryophyllata essential oil: The novel nanoparticulate systems with broad-spectrum antimicrobial activity

Fazly Bazzaz BS, Khameneh B, Namazi N, Iranshahi M, Davoodi D, Golmohammadzadeh S Letters in Applied Microbiology, 2018 ABSTRACT: In the present study, solid lipid nanoparticles containing Eugenia caryophyllata essential oil (SLN-EO) were prepared by high-shear homogenization and ultrasound methods, and used to eradicate pathogens. SLN formulations were evaluated for their size, zeta potential and… Read more »

Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents

Maruoka T, Kitanaka A, Kubota Y, Yamaoka G, Kameda T, Imataki O, Dobashi H, Bandoh S, Kadowaki N, Tanaka T International Journal of Oncology, 2018 ABSTRACT: Small-cell lung cancer (SCLC) is intractable due to its high propensity for relapse. Novel agents are thus needed for SCLC treatment. Lemongrass essential oil (LG-EO) and its major constituent,… Read more »

Antinociceptive Activity of Inula britannica L. and Patuletin: In vivo and Possible Mechanisms Studies

Zarei M, Mohammadi S, Komaki A Journal of Ethnopharmacology, 2018 ABSTRACT: ETHNOPHARMACOLOGICAL RELEVANCE: INULA BRITANNICA: L. (IBL) is a predominant medicinal plant traditionally utilized in the treatments of arthritis and back pain in Iranian folk medicine. AIM OF THE STUDY: The purpose of this research was to evaluate the analgesic effects of Inula britannica L…. Read more »

Cananga odorata essential oil reverses the anxiety induced by 1-(3-chlorophenyl) piperazine through regulating the MAPK pathway and serotonin system in mice

Zhang N, Zhang L, Feng L, Yao L Journal of Ethnopharmacology, 2018 ABSTRACT: ETHNOPHARMACOLOGICAL RELEVANCE: Cananga odorata essential oil, known as ylang-ylang essential oil (YYO), was commonly used in the aromatherapy for relaxation and mood adjusting use. In our previous study, YYO played anxiolytic effects on the mice in several behavioral tests that based on… Read more »

The antifungal activity of essential oil from Melaleuca leucadendra (L.) L. grown in China and its synergistic effects with conventional antibiotics against Candida

Zhang J, Wu H, Jiang D, Yang Y, Tang W, Xu K Natural Product Research, 2018 ABSTRACT: To identify the natural antifungal agents, the antifungal activities of Melaleuca leucadendra (L.) L. essential oil (ML-EO) from Fujian Province of China were assayed. Treatment of ML-EO in combination with the front-line using antibiotics against Candida led to… Read more »