Shahina Z, El-Ganiny AM, Minion J, Whiteway M, Sultana T, Dahms TES Fungal Biology and Biotechnology, 2018 ABSTRACT: BACKGROUND: Cinnamon (Cinnamomum zeylanicum) bark extract exhibits potent inhibitory activity against Candida albicans but the antifungal mechanisms of this essential oil remain largely unexplored. RESULTS: We analyzed the impact of cinnamon bark oil on C. albicans RSY150,… Read more »
Chemical composition analysis and in vitro biological activities of ten essential oils in human skin cells
Han X, Beaumont C, Stevens N Biochimie Open, 2017 ABSTRACT: Research on the biological effects of essential oils on human skin cells is scarce. In the current study, we primarily explored the biological activities of 10 essential oils (nine single and one blend) in a pre-inflamed human dermal fibroblast system that simulated chronic inflammation. We… Read more »
Lemongrass (Cymbopogon flexuosus) essential oil demonstrated anti-inflammatory effect in pre-inflamed human dermal fibroblasts
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: Lemongrass (Cymbopogon flexuosus) essential oil (LEO), which has citral as its main component, has exhibited anti-inflammatory effect in both animal and human cells. In this study, we evaluated the anti-inflammatory activity of a commercially available LEO in pre-inflamed human dermal fibroblasts. We first studied the impact of… Read more »
Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano (Origanum vulgare) essential oil in a human skin disease model
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: The use of oregano (Origanum vulgare) essential oil (OEO) has become popular in skin care products. However, scientific research regarding its effects on human skin cells is scarce. In this study, we investigated the biological activity of a commercially available OEO, which is high in carvacrol content,… Read more »
Arborvitae (Thuja plicata) essential oil significantly inhibited critical inflammation- and tissue remodeling-related proteins and genes in human dermal fibroblasts
Han X, Parker TL Biochimie Open, 2017 ABSTRACT: Arborvitae (Thuja plicata) essential oil (AEO) is becoming increasingly popular in skincare, although its biological activity in human skin cells has not been investigated. Therefore, we sought to study AEO’s effect on 17 important protein biomarkers that are closely related to inflammation and tissue remodeling by using… Read more »
Biological activities of frankincense essential oil in human dermal fibroblasts
Han X, Rodriguez D, Parker TL Biochimie Open, 2017 ABSTRACT: Although frankincense essential oil (FREO) has become increasingly popular in skin care, research on its biological activities in human skin cells is scarce, if not completely absent. In the current study, we explored the biological activities of FREO in pre-inflamed human dermal fibroblasts by analyzing… Read more »
The Neuroprotective Effects of Cinnamic Aldehyde in an MPTP Mouse Model of Parkinson’s Disease
Bae WY, Choi JS, Jeong JW International Journal of Molecular Sciences, 2018 ABSTRACT: Cinnamic aldehyde (CA), a key flavor compound in cinnamon essential oil, has been identified as an anti-oxidant, anti-angiogenic, and anti-inflammatory material. Recently, the neuroprotective effects of CA have been reported in various neurodegenerative disorders, including Parkinson’s disease (PD). In neurons, autophagy is… Read more »
Role of Essential Oil of Mentha Spicata (Spearmint) in Addressing Reverse Hormonal and Folliculogenesis Disturbances in a Polycystic Ovarian Syndrome in a Rat Model
Sadeghi Ataabadi M, Alaee S, Bagheri MJ, Bahmanpoor S Advanced Pharmaceutical Bulletin, 2017 ABSTRACT: Purpose: Given the antiandrogenic effects of spearmint, in this study we evaluated the effects of its essential oil on polycystic ovarian syndrome in a rat model. Methods: Female rats were treated as follows: Control, normal rats which received 150 mg/kg spearmint… Read more »
Alcoholic monoterpenes found in essential oil of aromatic spices reduce allergic inflammation by the modulation of inflammatory cytokines
Pina LTS, Ferro JNS, Rabelo TK, Oliveira MA, Scotti L, Scotti MT, Walker CIB, Barreto EO, Quintans Júnior LJ, Guimarães AG Natural Product Research, 2018 ABSTRACT: Allergic inflammation is a response of the body against pathogens by cytokine release and leucocyte recruitment. Recently, there was an increase in morbimortality associated with allergic inflammation, especially asthma…. Read more »
Effects of lemongrass oil and citral on hepatic drug-metabolizing enzymes, oxidative stress, and acetaminophen toxicity in rats
Li CC, Yu HF, Chang CH, Liu YT, Yao HT Journal of Food and Drug Analysis, 2018 ABSTRACT: The essential oil from a lemongrass variety of Cymbopogon flexuosus [lemongrass oil (LO)] is used in various food and aroma industry products and exhibits biological activities, such as anticancer and antimicrobial activities. To investigate the effects of… Read more »