Ota M, Sato N, Sone D, Ogura J, Kunugi H
Indian Journal of Psychiatry, 2017
BACKGROUND:
Although aromatherapy is widely used, the pharmacology of the essential oils remains undiscovered.
AIM:
The present study assessed the effect of (-)-linalool, the main contained material of lavender, on the brain function.
MATERIALS AND METHODS:
Healthy male volunteers calculated the regional cerebral blood flow (CBF) before and after inhalation of (-)-linalool, and CBF changes were evaluated.
RESULTS:
There were significant CBF reductions in the right superior temporal gyrus to insula, anterior cingulate cortex after inhalation.
CONCLUSIONS:
The previous study detected the regulatory influence of (-)-linalool on the glutamatergic transmission. The effect of (-)-linalool on the ACC and insula would cause the sedative and anxiolytic activity.
CITATION:
Ota M, Sato N, Sone D et al. (-)-Linalool influence on the cerebral blood flow in healthy male volunteers revealed by three-dimensional pseudo-continuous arterial spin labeling. Indian J Psychiatry. 2017 Apr-Jun;59(2):225-227. doi: 10.4103/psychiatry.IndianJPsychiatry_323_16.
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