Anti-edematogenic and anti-inflammatory activity of the essential oil from Croton rhamnifolioides leaves and its major constituent 1,8-cineole (eucalyptol)

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Martins AOBPB, Rodrigues LB, Cesário FRAS, de Oliveira MRC, Tintino CDM, Castro FFE, Alcântara IS, Fernandes MNM, de Albuquerque TR, da Silva MSA, de Sousa Araújo AA, Júniur LJQ, da Costa JGM, de Menezes IRA, Wanderley AG Biomedicine & Pharmacotherapy, 2017 ABSTRACT: The species Croton rhamnifolioides, belonging to the Croton genus, is known in ethnomedicine… Read more »

Intranasal co-administration of 1,8-cineole with influenza vaccine provide cross-protection against influenza virus infection

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Li Y, Xu YL, Lai YN, Liao SH, Liu N, Xu PP Phytomedicine, 2017 BACKGROUND: Vaccination is the most efficient means for protection against influenza. However, the various vaccines have low efficacy to protect against pandemic strains because of antigenic drift and recombination of influenza virus. Adjuvant therapy is one of the attempts to improve… Read more »

Molecular cloning and functional characterization of a monoterpene synthase isolated from the aromatic wild shrub Thymus albicans

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Filipe A, Cardoso JCR, Miguel G, Anjos L, Trindade H, Figueiredo AC, Barroso J, Power DM, Marques NT Journal of Plant Physiology, 2017 ABSTRACT: The essential oil of Thymus albicans Hoffmanns. & Link, a native shrub from the Iberian Peninsula, is mainly composed of monoterpenes. In this study, a 1,8-cineole synthase was isolated from the 1,8-cineole chemotype. A partial sequence that lacked the complete plastid… Read more »

Genetic diversity and metabolic profile of Salvia officinalis populations: implications for advanced breeding strategies

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Sarrou E, Ganopoulos I, Xanthopoulou A, Masuero D, Martens S, Madesis P, Mavromatis A, Chatzopoulou P Planta, 2017 ABSTRACT: MAIN CONCLUSION: As a result of this work, we were able to characterize seven indigenous to Greece Salvia officinalis populations using genetic and metabolomic tools. These tools can be used to select the most promising genotypes, capable to… Read more »

Genetic diversity and metabolic profile of Salvia officinalis populations: implications for advanced breeding strategies

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Sarrou E, Ganopoulos I, Xanthopoulou A, Masuero D, Martens S, Madesis P, Mavromatis A, Chatzopoulou P Planta, 2017 ABSTRACT: MAIN CONCLUSION: As a result of this work, we were able to characterize seven indigenous to Greece Salvia officinalis populations using genetic and metabolomic tools. These tools can be used to select the most promising genotypes,… Read more »

The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage

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Dörsam B, Wu CF, Efferth T, Kaina B, Fahrer J Archives of toxicology, 2015 ABSTRACT: The natural compound 1,8-cineol, also known as eucalyptol, is a major constituent of eucalyptus oil. This epoxy-monoterpene is used as flavor and fragrance in consumer goods as well as medical therapies. Due to its anti-inflammatory properties, 1,8-cineol is also applied… Read more »