Han X, Price R, Parker TL Cogent Medicine, 2017 ABSTRACT: Despite growing scientific evidence that essential oils possess important therapeutic benefits, research on their biological activities in complex human disease models is scarce. To enhance understanding in this regard, we analyzed the biological activities of an essential oil blend (EOB) in validated human cocultures with… Read more »
Anti-inflammatory activity of Juniper (Juniperus communis) berry essential oil in human dermal fibroblasts
Han X, Parker TL Cogent Medicine, 2017 ABSTRACT: Although juniper (Juniperus communis) berry essential oil (JEO) has been used in skin care products, research on its biological activity in human skin cells is scarce. In the current study, we explored the biological activity of JEO (with alpha-pinene as the major active component) in pre-inflamed human dermal… Read more »
Essential oils and their constituents as anticancer agents: a mechanistic view
Gautam N, Mantha AK, Mittal S BioMed Research International, 2014 ABSTRACT: Exploring natural plant products as an option to find new chemical entities as anticancer agents is one of the fastest growing areas of research. Recently, in the last decade, essential oils (EOs) have been under study for their use in cancer therapy and the… Read more »
Antitumor phenylpropanoids found in essential oils
Carvalho AA, Andrade LN, de Sousa ÉB, de Sousa DP Biomed Research International, 2015 ABSTRACT: The search for new bioactive substances with anticancer activity and the understanding of their mechanisms of action are high-priorities in the research effort toward more effective treatments for cancer. The phenylpropanoids are natural products found in many aromatic and medicinal… Read more »
Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cells In Vitro and In Vivo
Lu X, Yang L, Lu C, Xu Z, Qiu H, Wu J, Wang J, Tong J, Zhu Y, Shen J BioMed Research International, 2016 ABSTRACT: Nowadays, chemotherapy is still the main effective treatment for cancer. Herb prescriptions containing Pogostemon cablin Benth (also known as “Guang-Huo-Xiang”) have been widely used in Chinese medicine today. In our… Read more »
Ligands for cannabinoid receptors, promising anticancer agents
Nikan M, Nabavi SM, Manayi A Life Sciences, 2016 ABSTRACT: Cannabinoid compounds are unique to cannabis and provide some interesting biological properties. These compounds along with endocannabinoids, a group of neuromodulator compounds in the body especially in brain, express their effects by activation of G-protein-coupled cannabinoid receptors, CB1 and CB2. There are several physiological properties… Read more »
Zingiberene attenuates hydrogen peroxide-induced toxicity in neuronal cells
Togar B, Türkez H, Stefano AD, Tatar A, Cetin D Human & experimental toxicology, 2015 ABSTRACT: In this experimental design, we explored the neuroprotective potential of zingiberene (ZGB), a monocyclic sesquiterpene, in hydrogen peroxide (H2O2)-induced toxicity in newborn rat cerebral cortex cell cultures for the first time. The rats were exposed to H2O2 for 6… Read more »
Anticancer attributes of desert plants: a review
Harlev E, Nevo E, Lansky EP, Lansky S, Bishayee A
Anti-Cancer Drugs, 2012
Composition, Cytotoxic and Antimicrobial Activities of Satureja intermedia C.A.Mey Essential Oil
Sharifi-Rad J, Sharifi-Rad M, Hoseini-Alfatemi SM, Iriti M, Sharifi-Rad M, Sharifi-Rad M
International Journal of Molecular Sciences, 2015
Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde
Long M, Tao S, Rojo de la Vega M, Jiang T, Wen Q, Park SL, Zhang DD, Wondrak GT
Cancer Prevention Research (Philadelphia, Pa.), 2015