Efficacy of bergamot: From anti-inflammatory and anti-oxidative mechanisms to clinical applications as preventive agent for cardiovascular morbidity, skin diseases, and mood alterations

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Perna S, Spadaccini D, Botteri L, Girometta C, Riva A, Allegrini P, Petrangolini G, Infantino V, Rondanelli M Food Science & Nutrition, 2019 ABSTRACT: We summarize the effects of bergamot (extract, juice, essential oil, and polyphenolic fraction) on cardiovascular, bone, inflammatory, skin diseases, mood alteration, anxiety, pain, and stress. This review included a total of… Read more »

Antihyperlipidemic and anti-hyperglycemic effects of Cymbopogon jwarancusa in high-fat high-sugar diet model

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Khan SJ, Afroz S, Khan RA Pakistan Journal of Pharmaceutical Sciences, 2018 ABSTRACT: Hyperlipidemia is the root cause for development of atherosclerosis, coronary heart disease, diabetes mellitus, obesity, hypertension and cerebral palsy. Cymbopogon jwarancusa is an aromatic grass (Rusha grass, khavi grass) belonging to family Poaceaea. C. jwarancusa essential oil is famous for its use… Read more »

Thymol reduces oxidative stress, aortic intimal thickening, and inflammation-related gene expression in hyperlipidemic rabbits

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Yua YM, Chaob TY, Changb WC, Changb MJ, Leea MF Journal of Food and Drug Analysis, 2016 ABSTRACT: Atherosclerosis plays a key role in the development of cardiovascular diseases, and is often associated with oxidative stress and local inflammation. Thymol, a major polyphenolic compound in thyme, exhibits antioxidant and anti-inflammatory properties. In this study, we… Read more »

Structural relationships and vasorelaxant activity of monoterpenes

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Lima TC, Mota MM, Barbosa-Filho JM, Viana Dos Santos MR, De Sousa DP Daru, 2012 ABSTRACT: Background and purpose of the study The hypotensive activity of the essential oil of Mentha x villosa and its main constituent, the monoterpene rotundifolone, have been reported. Therefore, our objective was to evaluate the vasorelaxant effect of monoterpenes found… Read more »

The effects of Melissa officinalis (lemon balm) pretreatment on the resistance of the heart to myocardial injury

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Joukar S, Asadipour H, Sheibani M, Najafipour H, Dabiri S Pharmaceutical biology, 2016 ABSTRACT: CONTEXT: The antihyperlipidemic, antiarrhythmic, neuroprotective and hepatoprotective effects of Melissa officinalis L. (Lamiaceae) have been reported. However, no study has examined its effects on the resistance of the heart to stressful conditions. OBJECTIVE: The objective of this study is to evaluate… Read more »

Chemistry and Pharmacology of Citrus sinensis

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Favela-Hernández JM, González-Santiago O, Ramírez-Cabrera MA, Esquivel-Ferriño PC, Camacho-Corona Mdel R Molecules, 2016 ABSTRACT: Presently the search for new drugs from natural resources is of growing interest to the pharmaceutical industry. Natural products have been the source of new drugs since ancient times. Plants are a good source of secondary metabolites which have been found… Read more »

Biphasic cardiovascular and respiratory effects induced by β-citronellol

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Ribeiro-Filho HV, de Souza Silva CM, de Siqueira RJ, Lahlou S, Dos Santos AA, Magalhães PJ European journal of pharmacology, 2016 ABSTRACT: β-Citronellol is a monoterpene found in the essential oil of various plants with antihypertensive properties. In fact, β-citronellol possesses hypotensive actions due to its vasodilator abilities. Here we aimed to show that β-citronellol… Read more »

Linalool elicits vasorelaxation of mouse aortae through activation of guanylyl cyclase and K+ channels

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Kang P, Seol GH The Journal of pharmacy and pharmacology, 2015 ABSTRACT: OBJECTIVES: The aim of this study was to investigate the cardiovascular relaxing properties of monoterpene alcohol (-)-linalool (LIN), a principal component of several aromatic plants. METHODS: We assessed the effects of LIN on vascular contractility in mouse aortae and evaluated its underlying mechanisms… Read more »