Ogaly HA, Eltablawy NA, Abd-elsalam RM Oxidative Medicine and Cellular Longevity, 2018 ABSTRACT: Essential oils of some aromatic plants provide an effective nonmedicinal option to control liver fibrosis. Mentha piperita L. essential oil (MPEO) have been reported to possess protective effects against hepatotoxicity. However, its effect against liver fibrosis remains unknown. The present study investigated… Read more »
Gene co-expression networks in liver and muscle transcriptome reveal sex-specific gene expression in lambs fed with a mix of essential oils
Sabino M, Carmelo VAO, Mazzoni G, Cappelli K, Capomaccio S, Ajmone-Marsan P, Verini-Supplizi A, Trabalza-Marinucci M, Kadarmideen HN BMC Genomics, 2018 ABSTRACT: BACKGROUND: Essential oil (EO) dietary supplementation is a new strategy to improve animal health. EO compounds have antiparasitic, antimicrobial, antiviral, antimycotic, antioxidant and anti-inflammatory proprieties. Nutrigenomics investigations represent innovative approaches in understanding the… Read more »
Plants and Surgery: The Protective Effects of Thymoquinone on Hepatic Injury-A Systematic Review of In Vivo Studies
Tekbas A, Huebner J, Settmacher U, Dahmen U International Journal of Molecular Sciences, 2018 ABSTRACT: Multimodal treatment concepts including liver transplantation for hepatocellular carcinoma (HCC), extended resection methods and neoadjuvant chemotherapy for colorectal liver metastasis significantly improve patients’ outcome. However, surgery-induced hepatic ischemia-reperfusion injury (IRI) and chemotherapy-associated hepatotoxicity result in hepatocellular damage and compromised liver… Read more »
Protective effects of Mentha piperita L. leaf essential oil against CCl4 induced hepatic oxidative damage and renal failure in rats
Bellassoued K, Ben Hsouna A, Athmouni K, van Pelt J, Makni Ayadi F, Rebai T, Elfeki A Lipids in Health and Disease, 2018 ABSTRACT: BACKGROUND: Mentha piperita L. is a flowering plant belonging to the Lamiaceae family. Mentha plants constitute one of the main valuable sources of essential oil used in foods and for medicinal… Read more »
Rosemary (Rosmarinus officinalis) essential oil components exhibit anti-hyperglycemic, anti-hyperlipidemic and antioxidant effects in experimental diabetes
Selmi S, Rtibi K, Grami D, Sebai H, Marzouki L Pathophysiology, 2017 INTRODUCTION: The present study aims to investigate the protective effects of Rosemary (Rosmarinus officinalis L.) essential oils (ROEO) against alloxan-induced diabetes and oxidative stress in rats. METHODS: The animals were divided into four groups: Healthy Control (HC); Diabetic Control (DC); Healthy+ROEO (H+ROEO) and Diabetic+ROEO (D+ROEO)…. Read more »
Role of geraniol against lead acetate-mediated hepatic damage and their interaction with liver carboxylesterase activity in rats
Ozkaya A, Sahin Z, Kuzu M, Saglam YS, Ozkaraca M, Uckun M, Yologlu E, Comakli V, Demirdag R, Yologlu S Archives of Physiology and Biochemistry, 2017 ABSTRACT: In this study, the effect of geraniol (50 mg/kg for 30 d), a natural antioxidant and repellent/antifeedant monoterpene, in a rat model of lead acetate-induced (500 ppm for 30 d) liver damage was evaluated…. Read more »
Melaleuca alternifolia anthelmintic activity in gerbils experimentally infected by Haemonchus contortus
Grando TH, Baldissera MD, Gressler LT, de Sá MF, Bortoluzzi BN, Schafer AS, Ebling RC, Raffin RP, Santos RC, Stefani LM, Vaucher R, Leal ML, Monteiro SG Experimental Parasitology, 2016 ABSTRACT: Gastrointestinal parasites are one of the biggest health problems faced in sheep, mainly due to their pathogenicity and resistance to drugs used to control… Read more »
The protective effects of carvacrol and thymol against paracetamol-induced toxicity on human hepatocellular carcinoma cell lines (HepG2)
Palabiyik SS, Karakus E, Halici Z, Cadirci E, Bayir Y, Ayaz G, Cinar I Human & experimental toxicology, 2016 ABSTRACT: Acetaminophen (APAP) overdose could induce liver damage and lead to acute liver failure. The treatment of APAP overdoses could be improved by new therapeutic strategies. Thymus spp., which has many beneficial effects and has been… Read more »
Repeated-doses and reproductive toxicity studies of the monoterpene 1,8-cineole (eucalyptol) in Wistar rats
Caldas GF, Limeira MM, Araújo AV, Albuquerque GS, Silva-Neto JD, Silva TG, Costa-Silva JH, Menezes IR, Costa JG, Wanderley AG Food and Chemical Toxicology, 2016 ABSTRACT: 1,8-cineole (eucalyptol) is widely used as an excipient in the pharmaceutical industry and as a food flavoring agent, thus providing significant potential for human exposure to the compound. We… Read more »
Unraveling the Rat Intestine, Spleen and Liver Genome-Wide Transcriptome after the Oral Administration of Lavender Oil by a Two-Color Dye-Swap DNA Microarray Approach
Kubo H, Shibato J, Saito T, Ogawa T, Rakwal R, Shioda S PloS one, 2015 ABSTRACT: The use of lavender oil (LO)–a commonly, used oil in aromatherapy, with well-defined volatile components linalool and linalyl acetate–in non-traditional medicine is increasing globally. To understand and demonstrate the potential positive effects of LO on the body, we have… Read more »