Lactoferrin, chitosan and Melaleuca alternifolia-natural products that show promise in candidiasis treatment

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Felipe LO, Júnior WFDS, Araújo KC, Fabrino DL Brazilian Journal of Microbiology, 2017 ABSTRACT: The evolution of microorganisms resistant to many medicines has become a major challenge for the scientific community around the world. Motivated by the gravity of such a situation, the World Health Organization released a report in 2014 with the aim of… Read more »

Melaleuca alternifolia Induces Heme Oxygenase-1 Expression in Murine RAW264.7 Cells through Activation of the Nrf2-ARE Pathway

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Lee SY, Chen PY, Lin JC, Kirkby NS, Ou CH, Chang TC American Journal of Chinese Medicine, 2017 ABSTRACT: Melaleuca alternifolia concentrate (MAC) is the refined essential oil of the Australian native plant Melaleuca alternifolia. MAC has been reported to suppress the production of pro-inflammatory cytokines in both murine RAW264.7 macrophages and human monocytes stimulated with lipopolysaccharide… Read more »

Antimicrobial synergism and cytotoxic properties of Citrus limon L., Piper nigrum L. and Melaleuca alternifolia (Maiden and Betche) Cheel essential oils

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Nikolić MM, Jovanović KK, Marković TL, Marković DL, Gligorijević NN, Radulović SS, Kostić M, Glamočlija JM, Soković MD Journal of Pharmacy and Pharmacology, 2017 OBJECTIVES: The chemical composition, antimicrobial and synergistic effect, and cytotoxic activity of Citrus limon (lemon), Piper nigrum (green pepper) and Melaleuca alternifoila (tea tree) essential oils (EOs) were investigated. METHODS: Chemical analyses of essential oils were tested… Read more »

Melaleuca (Melaleuca alternifolia) essential oil demonstrates tissue-remodeling and metabolism-modulating activities in human skin cells

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Han X, Parker TL Cogent Biology, 2017 ABSTRACT: Melaleuca (Melaleuca alternifolia) essential oil (MEO), commonly known as tea tree oil, is popularly used in skincare products. In the current study, we investigated the biological activity of a commercially available MEO (with terpinen-4-ol as the major active component) in pre-inflamed human dermal fibroblasts, which were designed… Read more »

Melaleuca alternifolia anthelmintic activity in gerbils experimentally infected by Haemonchus contortus

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Grando TH, Baldissera MD, Gressler LT, de Sá MF, Bortoluzzi BN, Schafer AS, Ebling RC, Raffin RP, Santos RC, Stefani LM, Vaucher R, Leal ML, Monteiro SG Experimental Parasitology, 2016 ABSTRACT: Gastrointestinal parasites are one of the biggest health problems faced in sheep, mainly due to their pathogenicity and resistance to drugs used to control… Read more »