Chromobacterium violaceum and Pseudomonas aeruginosa PAO1: Models for Evaluating Anti-Quorum Sensing Activity of Essential Oil and Its Main Component Terpinen-4-ol

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Noumi E, Merghni A, M Alreshidi M, Haddad O, Akmadar G, De Martino L, Mastouri M, Ceylan O, Snoussi M, Al-Sieni A, De Feo V Molecules, 2018 ABSTRACT: The problem of antibiotic resistance among pathogens encourages searching for novel active molecules. The aim of the research was to assay the anti-quorum sensing (anti-QS) and antibiofilm… Read more »

Plants of the Melaleuca Genus as Antimicrobial Agents: From Farm to Pharmacy

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Sharifi-Rad J, Salehi B, Varoni EM, Sharopov F, Yousaf Z, Ayatollahi SA, Kobarfard F, Sharifi-Rad M, Afdjei MH, Sharifi-Rad M, Iriti M Phytotherapy Research, 2017 ABSTRACT: Plants belonging to Melaleuca genus (Myrtaceae family) are native to Oceania, where they have been used for ages by Aborigine people in Australian traditional medicine, mainly because of their… Read more »

Terpinen-4-ol inhibits colorectal cancer growth via reactive oxygen species

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Nakayama K, Murata S, Ito H, Iwasaki K, Villareal MO, Zheng YW, Matsui H, Isoda H, Ohkohchi N Oncology Letters, 2017 ABSTRACT: Terpinen-4-ol (TP4O) is the main component of the essential oil extracted from Melaleuca alternifolia, known as the tea tree, of the botanical family Myrtaceae. The anticancer effects of TP4O have been reported in several cancer cell… Read more »

Studies on the Behavior of Eucalyptol and Terpinen-4-ol – Natural Food Additives and Ecological Pesticides – in Model Lipid Membranes

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Hąc-Wydro K, Flasiński M, Broniatowski M, Sołtys M Langmuir, 2017 ABSTRACT: Effective application of the essential oils requires detailed exploration of their mechanism of action and the origin of diverse activity of their components. In this work, the influence of eucalyptol and terpinen-4-ol on artificial membranes was studied to verify whether the differences in the activity of these compounds are… Read more »

Melaleuca (Melaleuca alternifolia) essential oil demonstrates tissue-remodeling and metabolism-modulating activities in human skin cells

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Han X, Parker TL Cogent Biology, 2017 ABSTRACT: Melaleuca (Melaleuca alternifolia) essential oil (MEO), commonly known as tea tree oil, is popularly used in skincare products. In the current study, we investigated the biological activity of a commercially available MEO (with terpinen-4-ol as the major active component) in pre-inflamed human dermal fibroblasts, which were designed… Read more »

The influence of environmentally friendly pesticide – Eucalyptol – alone and in combination with terpinen-4-ol – on model bacterial membranes

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Hąc-Wydro K, Szydło K Colloids and surfaces. B, Biointerfaces, 2016 ABSTRACT: Eucalyptus oil is known from antimicrobial properties and due to natural origin and low toxicity it can be applied as a green pesticide. This plant extract is a mixture of compounds among which Eucalyptol prevails strongly over the number of minor components including terpinen-4-ol…. Read more »

Plant essential oils for pest and disease management

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Murray B Isman Crop Protection, 2000 ABSTRACT: Certain essential plant oils, widely used as fragrances and flavors in the perfume and food industries, have long been reputed to repel insects. Recent investigations in several countries confirm that some plant essential oils not only repel insects, but have contact and fumigant insecticidal actions against specific pests,… Read more »