Protective effect of essential oil from Citrus limon against aspirin-induced toxicity in rats

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Bouzenna H, Samout N, Dhibi S, Mbarki S, Akermi S, Khdhiri A, Elfeki A, Hfaiedh N Human & Experimental Toxicology, 2018 ABSTRACT: The present study is planned to examine the antioxidant activity (AA) and the protective effect of the essential oil of Citrus limon (EOC) against aspirin-induced histopathological changes in the brain, lung, and intestine… Read more »

Therapeutic potential of Citronella Essential Oil: a review

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Sharma R, Rao R, Kumar S, Mahant S, Khatkar S Current Drug Discovery Technologies, 2018 ABSTRACT: Mosquito borne diseases such as malaria, filariasis, chikunguniya, yellow fever, dengue and Japanese encephalitis are the major cause of remarkable morbidity and mortality in livestock and humans worldwide. Since ancient times, aromatic plants are used for their medicinal value…. Read more »

Toxicities of Selected Essential Oils, Silicone Oils, and Paraffin Oil against the Common Bed Bug (Hemiptera: Cimicidae)

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Zha C, Wang C, Li A Journal of Economic Entomology ABSTRACT: The common bed bug [Cimex lectularius L. (Hemiptera: Cimicidae)] and tropical bed bug [Cimex hemipterus F. (Hemiptera: Cimicidae)] resurged in the United States and many other countries over the past decades. The need for safe and effective bed bug control products propelled the development… Read more »

Chemical characterization, toxicology and mechanism of gastric antiulcer action of essential oil from Gallesia integrifolia (Spreng.) Harms in the in vitro and in vivo experimental models

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Arunachalam K, Balogun SO, Pavan E, de Almeida GVB, de Oliveira RG, Wagner T, Cechinel Filho V, de Oliveira Martins DT Biomedicine & Pharmacotherapy, 2017 ABSTRACT: Gallesia integrifolia is a Brazilian Amazon tree whose bark decoction is popularly used to treat peptic ulcer. The essential oil from the inner stem bark of G. integrifolia (EOGi) was chemically characterized by GC/MS. The in vitro cytotoxicity… Read more »

Chemical composition, acute toxicity, antioxidant and anti-inflammatory activities of Moroccan Tetraclinis articulata L

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El Jemli M, Kamal R, Marmouzi I, Doukkali Z, Bouidida EH, Touati D, Nejjari R, El Guessabi L, Cherrah Y, Alaoui K Journal of Traditional and Complementary Medicine, 2017 ABSTRACT: Hydro-distilled essential oil (EO) from the leaves of the western Mediterranean and Moroccan endemic plant Tetraclinis articulata was analyzed by GC/MS and examined for its acute toxicity on mice, in order to establish the safe doses. Furthermore, the… Read more »

Repeated-doses and reproductive toxicity studies of the monoterpene 1,8-cineole (eucalyptol) in Wistar rats

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Caldas GF, Limeira MM, Araújo AV, Albuquerque GS, Silva-Neto JD, Silva TG, Costa-Silva JH, Menezes IR, Costa JG, Wanderley AG Food and Chemical Toxicology, 2016 ABSTRACT: 1,8-cineole (eucalyptol) is widely used as an excipient in the pharmaceutical industry and as a food flavoring agent, thus providing significant potential for human exposure to the compound. We… Read more »

Herbal bioactivation: the good, the bad and the ugly

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Zhou S, Koh HL, Gao Y, Gong ZY, Lee EJ Life sciences, 2004 ABSTRACT: It has been well established that the formation of reactive metabolites of drugs is associated with drug toxicity. Similarly, there are accumulating data suggesting the role of the formation of reactive metabolites/intermediates through bioactivation in herbal toxicity and carcinogenicity. It has… Read more »