Identification and analysis of miRNAs and their targets in ginger using bioinformatics approach

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Singh N, Srivastava S, Sharma A Gene, 2015 ABSTRACT: MicroRNAs (miRNAs) are a large family of endogenous small RNAs derived from the non-protein coding genes. miRNA regulates the gene expression at the post-transcriptional level and plays an important role in plant development. Zingiber officinale is an important medicinal plant having numerous therapeutic properties. Its bioactive… Read more »

Zingiberene attenuates hydrogen peroxide-induced toxicity in neuronal cells

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Togar B, Türkez H, Stefano AD, Tatar A, Cetin D Human & experimental toxicology, 2015 ABSTRACT: In this experimental design, we explored the neuroprotective potential of zingiberene (ZGB), a monocyclic sesquiterpene, in hydrogen peroxide (H2O2)-induced toxicity in newborn rat cerebral cortex cell cultures for the first time. The rats were exposed to H2O2 for 6… Read more »

Cytotoxicity and genotoxicity of zingiberene on different neuron cell lines in vitro

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Togar B, Turkez H, Tatar A, Hacimuftuoglu A, Geyikoglu F Cytotechnology, 2015 ABSTRACT: The main objective of this study is to investigate the cytotoxic, genotoxic and antioxidant properties of zingiberene (ZBN) in an in vitro rat brain cell culture study. The cytotoxic effect was determined against the rat neuron and N2a neuroblastoma (N2a-NB) cell lines… Read more »