Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M
Dermatology, 2013
ABSTRACT:
BACKGROUND:
The antifungal activity of coriander oil has already been demonstrated in vitro.
OBJECTIVE:
Evaluation of the efficacy and tolerability of 6% coriander oil in unguentum leniens in the treatment of interdigital tinea pedis. Methods: Half-side comparative pilot study on subjects with symmetric, bilateral interdigital tinea pedis. Active drug and placebo control were applied twice daily on the affected areas, and follow-up visits were performed on days 14 and 28.
RESULTS:
40 participants (mean age 52.5 years, 60% male) were included in the study. For 6% coriander oil in unguentum leniens, a highly significant improvement of the clinical signs (p < 0.0001) was observed during the entire observation period; the number of positive fungal cultures also tended to decrease (p = 0.0654). The tolerability of the tested substances was good.
CONCLUSION:
Coriander oil is effective and well tolerated in the treatment of interdigital tinea pedis.
CITATION:
Beikert FC, Anastasiadou Z, Fritzen B, et al. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51.
[maxbutton id=”1042″]