Satou T, Ogawa Y, Koike Kazuo Phytother Res, 2015 ABSTRACT: We previously reported finding anxiolytic-like activity for sandalwood oil after administration in mice. In this report, we further investigated the emotional behavior associated with inhaled or intraperitoneally administered (+)-α-santalol, the main component of sandalwood oil, in addition to examining whether pharmacological or neurological transfers are… Read more »
α- and β-Santalols Directly Interact with Tubulin and Cause Mitotic Arrest and Cytotoxicity in Oral Cancer Cells
Lee B, Bohmann J, Reeves T, Levenson C, Risinger AL Journal of natural products, 2015 ABSTRACT: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, with no major advancements in treatment over the past 40 years. The current study explores the biological effects of East Indian sandalwood oil (EISO) and… Read more »
The Effects of Aroma Foot Massage on Blood Pressure and Anxiety in Japanese Community-Dwelling Men and Women: A Crossover Randomized Controlled Trial
Eguchi E, Funakubo N, Tomooka K, Ohira T, Ogino K, Tanigawa T PloS one, 2016 ABSTRACT: OBJECTIVES: The aim of this study was to investigate the effects of aroma foot massage on blood pressure, anxiety, and health-related quality of life (QOL) in Japanese community-dwelling men and women using a crossover randomized controlled trial. METHODS: Fifty-seven… Read more »
Estimation of the binding modes with important human cytochrome P450 enzymes, drug interaction potential, pharmacokinetics, and hepatotoxicity of ginger components using molecular docking, computational, and pharmacokinetic modeling studies
Qiu JX, Zhou ZW, He ZX, Zhang X, Zhou SF, Zhu S Drug design, development and therapy, 2015 ABSTRACT: Ginger is one of the most commonly used herbal medicines for the treatment of numerous ailments and improvement of body functions. It may be used in combination with prescribed drugs. The coadministration of ginger with therapeutic… Read more »
Anxiolytic Effect of Citrus aurantium L. on Patients with Chronic Myeloid Leukemia
Pimenta FC, Alves MF, Pimenta MB, Melo SA, Almeida AA, Leite JR, Pordeus LC, Diniz Mde F, Almeida RN Phytotherapy research : PTR, 2016 ABSTRACT: The bone marrow aspiration procedure is used in hematological diseases and consists of a painful, invasive procedure causing anxiety-associated symptoms. The present study assessed the effect of Citrus aurantium L…. Read more »
Variation of terpenes in milk and cultured cream from Norwegian alpine rangeland-fed and in-door fed cows
Borge GI, Sandberg E, Øyaas J, Abrahamsen RK Food chemistry, 2016 ABSTRACT: The terpene content of milk and cream made from milk obtained from cows fed indoors, and by early or late grazing, in alpine rangeland farms in Norway, were analysed for three consecutive years. The main terpenes identified and semi-quantified were the monoterpenes β-pinene,… Read more »
Cinnamaldehyde modulates LPS-induced systemic inflammatory response syndrome through TRPA1-dependent and independent mechanisms
Mendes SJ, Sousa FI, Pereira DM, Ferro TA, Pereira IC, Silva BL, Pinheiro AJ, Mouchrek AQ, Monteiro-Neto V, Costa SK, Nascimento JL, Grisotto MA, da Costa R, Fernandes ES International immunopharmacology, 2016 ABSTRACT: Cinnamaldehyde is a natural essential oil suggested to possess anti-bacterial and anti-inflammatory properties; and to activate transient receptor potential ankyrin 1 (TRPA1)… Read more »
Plants traditionally used as mosquito repellents and the implication for their use in vector control
Tisgratog R, Sanguanpong U, Grieco JP, Ngoen-Kluan R, Chareonviriyaphap T Acta tropica, 2016 ABSTRACT: Numerous plants with insect repelling properties are native to the tropics where they are produced for a wide range of medicinal purposes. In Thailand, these native plant species have a history of use for personal protection against biting insects. From our… Read more »
Terpene arms race in the Seiridium cardinale – Cupressus sempervirens pathosystem
Ander Achotegui-Castells, Gianni Della Rocca, Joan Llusià, Roberto Danti, Sara Barberini, Mabrouk Bouneb, Sauro Simoni, Marco Michelozzi, Josep Peñuelas Scientific Reports, 2016 ABSTRACT: The canker-causing fungus Seiridium cardinale is the major threat to Cupressus sempervirens worldwide. We investigated the production of terpenes by canker-resistant and susceptible cypresses inoculated with S. cardinale, the effect of these… Read more »
Appetite-enhancing Effects of trans-Cinnamaldehyde, Benzylacetone and 1-Phenyl-2-butanone by Inhalation
Ogawa K, Ito M Planta medica, 2016 ABSTRACT: Fragrance in the air and odours of foods and drinks are reported to affect feeding behaviours of humans and other animals. Many previous studies focusing on the relationship between fragrance and appetite have described a reduction of food intake by fragrance administration to help prevent lifestyle diseases…. Read more »