Basha RH, Sankaranarayanan C Chemico-biological interactions, 2016 ABSTRACT: Oxidative and inflammatory stress has been implicated in the onset and progression of diabetes mellitus and its complications. The present study was designed to evaluate the effect of ß-Caryophyllene (BCP) on hyperglycemia mediated oxidative and inflammatory stress in streptozotocin (STZ) induced diabetic rats. Diabetes was induced in experimental… Read more »
Growth regulating properties of isoprene and isoprenoid-based essential oils
Jones AM, Shukla MR, Sherif SM, Brown PB, Saxena PK Plant cell reports, 2016 ABSTRACT: KEY MESSAGE: Essential oils have growth regulating properties comparable to the well-documented methyl jasmonate and may be involved in localized and/or airborne plant communication. Aromatic plants employ large amounts of resources to produce essential oils. Some essential oils are known… Read more »
Antimanic-like effects of (R)-(−)-carvone and (S)-(+)-carvone in mice
Nogoceke FP, Barcaro IM, de Sousa DP, Andreatini R Neuroscience letters, 2016 ABSTRACT: Carvone is a monoterpene that is present in spearmint (Mentha spicata) and caraway (Carum carvi) essential oils and has been shown to have anticonvulsant effects, likely through the blockade of voltage-gated sodium channels, and anxiolytic-like effects. Considering that some anticonvulsants that blocked… Read more »
Linalool elicits vasorelaxation of mouse aortae through activation of guanylyl cyclase and K+ channels
Kang P, Seol GH The Journal of pharmacy and pharmacology, 2015 ABSTRACT: OBJECTIVES: The aim of this study was to investigate the cardiovascular relaxing properties of monoterpene alcohol (-)-linalool (LIN), a principal component of several aromatic plants. METHODS: We assessed the effects of LIN on vascular contractility in mouse aortae and evaluated its underlying mechanisms… Read more »
Antinociceptive and antihyperglycemic effects of Melissa officinalis essential oil in an experimental model of diabetes
Hasanein P, Riahi H Medical Principles and Practice: International Journal of the Kuwait University, Health Science Center, 2015 ABSTRACT: OBJECTIVE: The efficacy of oral administration of Melissa officinlias essential oil (MOEO) on hyperalgesia was investigated using the formalin test in streptozotocin (STZ)-induced diabetic rats. MATERIALS AND METHODS: Animals were divided into control, MOEO-treated control (0.01,… Read more »
Identification of repellent odorants to the body louse, Pediculus humanus corporis, in clove essential oil
Iwamatsu T, Miyamoto D, Mitsuno H, Yoshioka Y, Fujii T, Sakurai T, Ishikawa Y, Kanzaki R Parasitology research, 2016 ABSTRACT: The control of body lice is an important issue for human health and welfare because lice act as vectors of disease such as typhus, relapsing fever, and trench fever. Body lice exhibit avoidance behavior to… Read more »
Dietary Geraniol by Oral or Enema Administration Strongly Reduces Dysbiosis and Systemic Inflammation in Dextran Sulfate Sodium-Treated Mice
Luigia De Fazio, Enzo Spisni, Elena Cavazza, Antonio Strillacci, Marco Candela, Manuela Centanni, Chiara Ricci, Fernando Rizzello, Massimo Campieri, Maria C. Valerii Frontiers in pharmacology, 2016 ABSTRACT: (Trans)-3,7-Dimethyl-2,6-octadien-1-ol, commonly called geraniol (Ge-OH), is an acyclic monoterpene alcohol with well-known anti-inflammatory, antitumoral, and antimicrobial properties. It is widely used as a preservative in the food industry… Read more »
Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer’s mice
Sabogal-Guáqueta AM, Osorio E, Cardona-Gómez GP Neuropharmacology, 2016 ABSTRACT: Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disorder. Several types of treatments have been tested to block or delay the onset of the disease, but none have been completely successful. Diet, lifestyle and natural products are currently the main scientific focuses. Here, we evaluate the… Read more »
Effects of monoterpenes on ion channels of excitable cells
Oz M, Lozon Y, Sultan A, Yang KH, Galadari S Pharmacology & therapeutics, 2015 ABSTRACT: Monoterpenes are a structurally diverse group of phytochemicals and a major constituent of plant-derived ‘essential oils’. Monoterpenes such as menthol, carvacrol, and eugenol have been utilized for therapeutical purposes and food additives for centuries and have been reported to have… Read more »
Unraveling the Rat Intestine, Spleen and Liver Genome-Wide Transcriptome after the Oral Administration of Lavender Oil by a Two-Color Dye-Swap DNA Microarray Approach
Kubo H, Shibato J, Saito T, Ogawa T, Rakwal R, Shioda S PloS one, 2015 ABSTRACT: The use of lavender oil (LO)–a commonly, used oil in aromatherapy, with well-defined volatile components linalool and linalyl acetate–in non-traditional medicine is increasing globally. To understand and demonstrate the potential positive effects of LO on the body, we have… Read more »