Fekrazad R, Afzali M, Pasban-Aliabadi H, Esmaeili-Mahani S, Aminizadeh M, Mostafavi A Brazilian Dental Journal, 2017 ABSTRACT: Identifying new chemotherapeutic agents with fewer side effects is a major concern for scientists today. Thymus caramanicus Jalas (Lamiaceae family) is one of the species of Thymus that grows wild in different regions of Iran. Traditionally, leaves of… Read more »
Integumentary System
This system includes the skin, hair, sweat glands, and nails. It protects the body against loss of water, abrasion and infection. Common disorders include skin cancer, warts, acne, burns, eczema, vitiligo, and psoriasis.
Composition of Volatile Oil and Methanolic Extract of Jordanian Melissa Officinals L. and Actions Againsthuman Cancer Cell Lines
Barakat SA, Hudaib M, EL-asadand N, Burns DT Oriental Journal of Chemistry, 2016 ABSTRACT: The essential oil of Jordanian Melissa officinalis L. were obtained by hydro-distillation and analyzed by Gas Chromatography – Mass Spectrometry. Components representing 96.40% of the total oil were identified. The methanolic extract and the volatile oil of Melissa officinalisL, were tested… Read more »
Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 Cells In Vitro and In Vivo
Lu X, Yang L, Lu C, Xu Z, Qiu H, Wu J, Wang J, Tong J, Zhu Y, Shen J BioMed Research International, 2016 ABSTRACT: Nowadays, chemotherapy is still the main effective treatment for cancer. Herb prescriptions containing Pogostemon cablin Benth (also known as “Guang-Huo-Xiang”) have been widely used in Chinese medicine today. In our… Read more »
Essential oils components as a new path to understand ion channel molecular pharmacology
de Araújo DA, Freitas C, Cruz JS Life sciences, 2011 ABSTRACT: The discovery and development of new drugs targeting voltage-gated ion channels are important for treating a variety of medical conditions and diseases. Ion channels are molecular nanostructures expressed ubiquitously throughout the whole body, and are involved in many basic physiological processes. Over the years,… Read more »
Inhibitory effects of rosemary (Rosemarinus officinalis L.) essential oil on pathogenicity of irradiated and non-irradiated Pseudomonas aeruginosa
Araby E, El-Tablawy SY Journal of photochemistry and photobiology. B, Biology. 2016 ABSTRACT: Pseudomonas aeruginosa is considered one of the most important opportunistic pathogens, which is responsible for nosocomial infections. The complex pathophysiology of infections associated with P. aeruginosa is due to its ability to grow in a biofilm mass and to produce a large… Read more »
Ligands for cannabinoid receptors, promising anticancer agents
Nikan M, Nabavi SM, Manayi A Life Sciences, 2016 ABSTRACT: Cannabinoid compounds are unique to cannabis and provide some interesting biological properties. These compounds along with endocannabinoids, a group of neuromodulator compounds in the body especially in brain, express their effects by activation of G-protein-coupled cannabinoid receptors, CB1 and CB2. There are several physiological properties… Read more »
Inhibition of melanogenesis by β-caryophyllene from lime mint essential oil in mouse B16 melanoma cells
Yang CH, Huang YC, Tsai ML, Cheng CY1, Liu LL, Yen YW, Chen WL International journal of cosmetic science, 2015 ABSTRACT: OBJECTIVE: Volatile essential oils of mint species are used for cosmetics and in skin care products. In this study, we evaluated the main chemical components of the lime mint and the anti-melanogenic properties of… Read more »
Therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products
Houël E, Gonzalez G, Bessière JM, Odonne G, Eparvier V, Deharo E, Stien D Memórias do Instituto Oswaldo Cruz, 2015 ABSTRACT: This study examined whether the antidermatophytic activity of essential oils (EOs) can be used as an indicator for the discovery of active natural products against Leishmania amazonensis. The aerial parts of seven plants were… Read more »
Cytotoxicity and genotoxicity of zingiberene on different neuron cell lines in vitro
Togar B, Turkez H, Tatar A, Hacimuftuoglu A, Geyikoglu F Cytotechnology, 2015 ABSTRACT: The main objective of this study is to investigate the cytotoxic, genotoxic and antioxidant properties of zingiberene (ZBN) in an in vitro rat brain cell culture study. The cytotoxic effect was determined against the rat neuron and N2a neuroblastoma (N2a-NB) cell lines… Read more »
Furanodiene enhances the anti-cancer effects of doxorubicin on ERα-negative breast cancer cells in vitro
Zhong ZF, Qiang WA, Wang CM, Tan W, Wang YT European journal of pharmacology, 2016 ABSTRACT: Furanodiene is a natural product isolated from Rhizoma curcumae, and exhibits broad-spectrum anti-cancer activities in vitro and in vivo. Our previous study proved that furanodiene could increase growth inhibition of steroidal agent in ERα-positive breast cancer cells, but whether… Read more »