Han X, Beaumont C, Rodriguez D, Bahr T Phytotherapy Research, 2018 ABSTRACT: Very few studies have investigated the biological activities of black pepper essential oil (BPEO) in human cells. Therefore, in the current study, we examined the biological activities of BPEO in cytokine-stimulated human dermal fibroblasts by analyzing the levels of 17 important protein biomarkers… Read more »
- Botanical Name: Piper nigrum
- Alternative Names: Peppercorn
- Botanical Family: Piperaceae
- Primary Constituent: Caryophyllene
- Other Main Constituents: Limonene, Carene , Beta-Pinene
- Distillation Method: Steam Distillation
- Plant Part: Fruit
Black pepper (Piper nigrum) essential oil demonstrates tissue remodeling and metabolism modulating potential in human cells
Han X, Beaumont C, Rodriguez D, Bahr T Phytotherapy Research, 2018 ABSTRACT: Very few studies have investigated the biological activities of black pepper essential oil (BPEO) in human cells. Therefore, in the current study, we examined the biological activities of BPEO in cytokine-stimulated human dermal fibroblasts by analyzing the levels of 17 important protein biomarkers… Read more »
In Vitro Evaluation of Essential Oils Derived from Piper nigrum (Piperaceae) and Citrus limonum (Rutaceae) against the Tick Rhipicephalus (Boophilus) microplus (Acari: Ixodidae)
Vinturelle R, Mattos C, Meloni J, Nogueira J, Nunes MJ, Vaz IS Jr, Rocha L, Lione V, Castro HC, Chagas EFD Biochemistry Research International, 2017 ABSTRACT: The present research aimed to study the chemical composition and acaricidal activity of Citrus limonum and Piper nigrum essential oils against the cattle tick Rhipicephalus microplus. GC-MS analysis of C. limonumessential oil showed limonene (50.3%), β-pinene (14.4%), and γ-terpinene… Read more »
Evaluation of antioxidant potential of essential oils of some commonly used Indian spices in in vitro models and in food supplements enriched with omega-6 and omega-3 fatty acids.
Bag A, Chattopadhyay RR Environmental Science and Pollution Research, 2017 ABSTRACT: The aim of this study was to evaluate and compare the antioxidant potential of essential oils of some commonly used Indian spices (black pepper, cinnamon, clove, coriander and cumin) in various in vitro models and in food supplements enriched with omega-6 and omega-3 fatty acids. In… Read more »
Comparative analysis of essential oil composition of Iranian and Indian Nigella sativa L. extracted using supercritical fluid extraction and solvent extraction
Ghahramanloo KH, Kamalidehghan B, Akbari Javar H, Teguh Widodo R, Majidzadeh K, Noordin MI Drug Design, Development and Therapy, 2017 ABSTRACT: The objective of this study was to compare the oil extraction yield and essential oil composition of Indian and Iranian Nigella sativa L. extracted by using Supercritical Fluid Extraction (SFE) and solvent extraction methods. In this study, a gas chromatography… Read more »
Prebiotic Potential and Chemical Composition of Seven Culinary Spice Extracts
Lu QY, Summanen PH, Lee RP, Huang J, Henning SM, Heber D, Finegold SM, Li Z Journal of Food Science, 2017 ABSTRACT: The objective of this study was to investigate prebiotic potential, chemical composition, and antioxidant capacity of spice extracts. Seven culinary spices including black pepper, cayenne pepper, cinnamon, ginger, Mediterranean oregano, rosemary, and turmeric were extracted with boiling water. Major chemical… Read more »
Neuroprotective Effects of β-Caryophyllene against Dopaminergic Neuron Injury in a Murine Model of Parkinson’s Disease Induced by MPTP
Viveros-Paredes JM, González-Castañeda RE, Gertsch J, Chaparro-Huerta V, López-Roa RI, Vázquez-Valls E, Beas-Zarate C, Camins-Espuny A, Flores-Soto ME Pharmaceuticals (Basel, Switzerland), 2017 ABSTRACT: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders and is characterized by the loss of dopaminergic neurons in the substantia nigra (SN). Although the causes of PD are not understood, evidence suggests that its pathogenesis is associated… Read more »
Aromatherapy and Essential Oils (PDQ®): Health Professional Version
PDQ Integrative, Alternative, and Complementary Therapies Editorial Board PDQ Cancer Information Summaries, 2017 EXCERPT: This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the use of aromatherapy and essential oils in the treatment of people with cancer. It is intended as a resource to inform and assist clinicians who care for cancer… Read more »
β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway
Cheng Y, Dong Z, Liu S Pharmacology, 2014 ABSTRACT: BACKGROUND/AIMS: The activation of cannabinoid receptor 2 (CB2) has the beneficial effect of reducing neuroinflammatory response in the treatment of Alzheimer’s disease (AD) and is suggested to trigger the peroxisome proliferator-activated receptor-γ (PPARγ) pathway; agonists of both receptors improve AD. Recently, the plant metabolite β-caryophyllene was… Read more »
Protective effects of trans-caryophyllene on maintaining osteoblast function
Shan J, Chen L, Lu K IUBMB Life, 2017 ABSTRACT: Age-related osteoblast dysfunction is the main cause of age-related bone loss. Trans-caryophyllene (TC) is an important constituent of the essential oils derived from several species of medicinal plants. In this study, we investigated the effects of TC on osteoblast function in osteoblastic MC3T3-E1 cells. The… Read more »