Sanna MD, Les F, Lopez V, Galeotti N Frontiers in Pharmacology, 2019 ABSTRACT: Low treatment efficacy represents an important unmet need in neuropathic pain patients and there is an urgent need to develop a more effective pharmacotherapy. An increasing number of patients choose complementary medicine to relieve pain. Lavender essential oil (LEO) is approved by… Read more »
Anti-depressive-like effect of 2-phenylethanol inhalation in mice
Ueno H, Shimada A, Suemitsu S, Murakami S, Kitamura N, Wani K, Matsumoto Y, Okamoto M, Ishihara T Biomedicine & Pharmacotherapy, 2018 ABSTRACT: Rose oil has traditionally been used to treat psychiatric disorders, but the scientific basis of this treatment remains poorly understood. The main odor component of rose oil is 2-phenylethanol (2-PE), but the… Read more »
Antidepressant-Like Effect of Lippia sidoides (Verbenaceae) Essential Oil and Its Major Compound Thymol in Mice
Parente MSR, Custódio FR, Cardoso NA, Lima MJA, Melo TS, Linhares MI, Siqueira RMP, Nascimento AÁD, Catunda Júnior FEA, Melo CTV Scientia Pharmaceutica, 2018 ABSTRACT: Depression is a common disease affecting more than 300 million people worldwide. Since Lippia sidoides has shown central nervous system effects in previous works, we aimed to investigate the effect… Read more »
Effects of oregano essential oil on brain TLR4 and TLR2 gene expression and depressive-like behavior in a rat model
Amiresmaeili A, Roohollahi S, Mostafavi A, Askari N Research in Pharmaceutical Sciences, 2018 ABSTRACT: The aim of the present study was to evaluate the effects of oregano essential oil (OEO) on the hippocampus and prefrontal cortex TLR 2/4 gene expression and depressive like behavior induced by chronic unpredictable stress (CUS). Sucrose preference and forced swim… Read more »
Essential Oils and Gastroparesis: Power for Transforming Health, Hope, and Quality of Life
Macoskey C, Dunn DJ Journal of Holistic Nursing Practice, 2017 ABSTRACT: This study explored how essential oils for persons with gastroparesis symptoms affect the quality of life. Gastroparesis is a chronic delayed gastric motility disorder characterized by postprandial fullness, early satiety, nausea, vomiting, abdominal discomfort, bloating, depression, and anxiety. The aim of this study was to determine… Read more »
Can Ocimum basilicum relieve chronic unpredictable mild stress-induced depression in mice?
Ayuob NN, Firgany AEL, El-Mansy AA, Ali S Experimental and Molecular Pathology BACKGROUND: Depression is one of the important world-wide health problems. OBJECTIVES: This study aimed to assess the ameliorative effect of Ocimum basilicum (OB) essential oil on the behavioral, biochemical and histopathological changes resulted from exposure to chronic unpredictable mild stress (CUMS). It also aimed to… Read more »
Chemistry and Pharmacology of Citrus sinensis
Favela-Hernández JM, González-Santiago O, Ramírez-Cabrera MA, Esquivel-Ferriño PC, Camacho-Corona Mdel R Molecules, 2016 ABSTRACT: Presently the search for new drugs from natural resources is of growing interest to the pharmaceutical industry. Natural products have been the source of new drugs since ancient times. Plants are a good source of secondary metabolites which have been found… Read more »
Linalool and beta-pinene exert their antidepressant-like activity through the monoaminergic pathway
Guzmán-Gutiérrez SL, Bonilla-Jaime H, Gómez-Cansino R, Reyes-Chilpa R. Life Sciences, 2015 ABSTRACT: AIMS: Linalool and β-pinene are two volatile monoterpenes that possess antidepressant-like activity. These are components of many aromatic plants used in folk medicine around the world to relieve anxiety and depression. In this contribution, we focused on examining the mechanism of action of… Read more »
β-Caryophyllene, a CB2 receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice
Bahi A, Al Mansouri S, Al Memari E, Al Ameri M, Nurulain SM, Ojha S
Physiology & Behavior, 2014
Aromatherapy and the central nerve system (CNS): therapeutic mechanism and its associated genes.
Lv XN, Liu ZJ, Zhang HJ, Tzeng CM
Current Drug Targets, 2013